Optimization of chemical shift selective suppression of fat.

Strategies to optimize flip angles for chemical shift selective fat suppression are discussed. Mathematical models for fat suppression in spoiled gradient recalled acquisition, spin echo, and RARE, which incorporate steady state conditions and multiple spectral components of fat, are developed. The optimal suppression flip angle is found to be larger than that determined with a single fat component model by more than 10 degrees due to contributions from unflipped components such as olefinic and glycerol protons that lie outside the suppression band.