Literature DB >> 9770010

[Synthesis and pharmacologic study of 1,5-benzodiazepine-2,4-diones and their alkyl derivatives].

A Zellou1, Y Cherrah, M Hassar, E M Essassi.   

Abstract

From the pharmacodynamic studies of 1,5-benzodiazepin-2,4-diones and alkyl derivatives prepared in our laboratories, we can conclude that these products are not toxic at therapeutic dosage. They have sedative, myorelaxant and anxiolytic actions. The two products alkylated by allyl bromide have also hypnotic, sedative and anticonvulsant properties.

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Year:  1998        PMID: 9770010

Source DB:  PubMed          Journal:  Ann Pharm Fr        ISSN: 0003-4509


  1 in total

1.  Synthesis and Pharmacological Valorization of Derivatives of 4-Phenyl-1,5-Benzodiazepin-2-One.

Authors:  Terence Nguema Ongone; Redouane Achour; Mostafa El Ghoul; Latifa El Ouasif; Khalid Taghzouti; Meryem El Jemli; Yahia Cherrah; Katim Alaoui; Amina Zellou
Journal:  Adv Pharmacol Sci       Date:  2018-04-01
  1 in total

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