Literature DB >> 9769448

Comorbidity and drug use in cognitively impaired elderly living in long-term care.

F Landi1, G Gambassi, K L Lapane, A Sgadari, D Gifford, V Mor, R Bernabei.   

Abstract

Cognitive impairment is associated with an increased mortality in older people. The prevalence and impact of comorbidity on functional status and mortality of demented patients has not been fully elucidated. Using a population-based data set, we describe the prevalence of cognitive impairment, functional status, principal comorbid conditions and 1-year survival for over 300,000 patients admitted to the nursing homes in five US states. Sixty-one percent of patients have some level of cognitive impairment, and this correlates with the degree of physical frailty. Severer cognitive impairment is associated with a higher mortality rate. Yet, patients with cognitive impairment appear to have fewer comorbid conditions and are less likely to receive medications and special treatments than residents with normal cognitive status. Additional studies are needed to understand whether demented patients may paradoxically be considered healthier or, instead, are only neglected.

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Year:  1998        PMID: 9769448     DOI: 10.1159/000017087

Source DB:  PubMed          Journal:  Dement Geriatr Cogn Disord        ISSN: 1420-8008            Impact factor:   2.959


  8 in total

1.  Predictors of mortality in patients with Alzheimer's disease living in nursing homes.

Authors:  G Gambassi; F Landi; K L Lapane; A Sgadari; V Mor; R Bernabei
Journal:  J Neurol Neurosurg Psychiatry       Date:  1999-07       Impact factor: 10.154

2.  Antithrombotic drugs in secondary stroke prevention among a community dwelling older population.

Authors:  F Landi; M Cesari; G Onder; V Zamboni; F Lattanzio; A Russo; C Barillaro; R Bernabei
Journal:  J Neurol Neurosurg Psychiatry       Date:  2003-08       Impact factor: 10.154

3.  Nursing-home residents and their drug use: a comparison between mentally intact and mentally impaired residents. The Bergen district nursing home (BEDNURS) study.

Authors:  Harald A Nygaard; Mala Naik; Sabine Ruths; Jørund Straand
Journal:  Eur J Clin Pharmacol       Date:  2003-08-12       Impact factor: 2.953

Review 4.  Adherence to medication in patients with dementia: predictors and strategies for improvement.

Authors:  Sönke Arlt; Reinhard Lindner; Alexander Rösler; Wolfgang von Renteln-Kruse
Journal:  Drugs Aging       Date:  2008       Impact factor: 3.923

5.  Prognosis and vascular co-morbidity in dementia a historical cohort study in general practice.

Authors:  L Meerman; E H van de Lisdonk; R T C M Koopmans; G A Zielhuis; M G M Olde Rikkert
Journal:  J Nutr Health Aging       Date:  2008-02       Impact factor: 4.075

6.  Effect of dementia on the use of drugs for secondary prevention of ischemic heart disease.

Authors:  Nicole R Fowler; Amber E Barnato; Howard B Degenholtz; Angela M Curcio; James T Becker; Lewis H Kuller; Oscar L Lopez
Journal:  J Aging Res       Date:  2014-02-25

7.  Identification and evaluation of existing nursing homes quality indicators.

Authors:  Katherine Berg; Vincent Mor; John Morris; Katharine M Murphy; Terry Moore; Yael Harris
Journal:  Health Care Financ Rev       Date:  2002

8.  Physical diagnoses in nursing home residents - is dementia or severity of dementia of importance?

Authors:  Live Bredholt Jørgensen; Berit Marie Thorleifsson; Geir Selbæk; Jūratė Šaltytė Benth; Anne-Sofie Helvik
Journal:  BMC Geriatr       Date:  2018-10-22       Impact factor: 3.921

  8 in total

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