| Literature DB >> 9767634 |
C Hubschwerlen1, P Angehrn, K Gubernator, M G Page, J L Specklin.
Abstract
A series of bridged monocyclic beta-lactams activated by various groups on the beta-lactam nitrogen (X = OCH2CO2H, OSO3H) has been synthesized and evaluated. Among them, the bridged sulfactams (X = OSO3H) were found to be effective beta-lactamase inhibitors. They inhibit both class A and class C beta-lactamases.Entities:
Mesh：
Substances：
Year: 1998 PMID： 9767634 DOI： 10.1021/jm9800245
Source DB: PubMed Journal: J Med Chem ISSN： 0022-2623 Impact factor: 7.446