Literature DB >> 9767095

Measurement of the extracellular H2O2 in the brain by microdialysis.

B Lei1, N Adachi, T Arai.   

Abstract

This paper reports on the protocol for the determination of H2O2 in the brain using in vivo microdialysis coupled with fluorometry of dichlorofluorescin oxidation. We applied this protocol to monitor changes in the concentration of H2O2 in the brain, in vivo, during ischemia and reperfusion. Using this method, changes in the level of H2O2 in the brain during ischemia and reperfusion were effectively determined. The present protocol provides a novel tool to study the production of reactive oxygen species in the brain. Copyright 1998 Elsevier Science B.V.

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Year:  1998        PMID： 9767095     DOI： 10.1016/s1385-299x(98)00018-x

Source DB:  PubMed          Journal:  Brain Res Brain Res Protoc        ISSN： 1385-299X


  13 in total

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Review 4.  Optical and pharmacological tools to investigate the role of mitochondria during oxidative stress and neurodegeneration.

Authors:  Kelley A Foster; Francesca Galeffi; Florian J Gerich; Dennis A Turner; Michael Müller
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6.  Hydrogen peroxide increases GABAergic mIPSC through presynaptic release of calcium from IP3 receptor-sensitive stores in spinal cord substantia gelatinosa neurons.

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Journal:  Eur J Neurosci       Date:  2007-02       Impact factor: 3.386

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9.  Design and synthesis of a ruthenium(II) complex-based luminescent probe for highly selective and sensitive luminescence detection of nitric oxide.

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10.  Postresuscitation N-acetylcysteine treatment reduces cerebral hydrogen peroxide in the hypoxic piglet brain.

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