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Literature DB >> 976639

Disappearance rate of endogenous human C-peptide from blood.

Abstract

Glucagon (1 mg) and glucose (60 ml of 50% solution) were infused over 60 min to three normal and one obese subjects and two insulinoma patients. Plasma C-peptide immunoreactivity (CPR) and immunoreactive insulin (IRI) increased during the infusion. Half time of CPR after cessation of the infusion was 20.1 +/- 4.0 min, and that of IRI 9.8 +/- 1.3 min, respectively. This difference partly explains the higher molar concentration in plasma of CPR than IRI.

Entities: Chemical Disease Gene Species

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Year: 1976 PMID： 976639 DOI： 10.1007/BF01219517

Source DB: PubMed Journal: Diabetologia ISSN： 0012-186X Impact factor: 10.122

8 in total

1. Human C-peptide in normal and diabetic subjects.

Authors: L G Heding; S M Rasmussen
Journal: Diabetologia Date: 1975-06 Impact factor: 10.122

2. Proinsulin, insulin, and C-peptide concentrations in human portal and peripheral blood.

Authors: D L Horwitz; J I Starr; M E Mako; W G Blackard; A H Rubenstein
Journal: J Clin Invest Date: 1975-06 Impact factor: 14.808

3. Disappearance of immunoreactive insulin in normal and adult-onset diabetic subjects.

Authors: L Stimmler
Journal: Diabetes Date: 1967-09 Impact factor: 9.461

4. Significance of disappearance-rate of injected insulin.

Authors: F I Martin; A E Stocks; M J Pearson
Journal: Lancet Date: 1967-03-18 Impact factor: 79.321

5. Plasma insulin responses to glucose in femoral, hepatic, and pancreatic veins in dogs.

Authors: Y Kanazawa; T Kuzuya; T Ide; K Kosaka
Journal: Am J Physiol Date: 1966-08

6. Diffusion of glucose, insulin, inulin, and Evans blue protein into thoracic duct lymph of man.

Authors: E A Rasio; C L Hampers; J S Soeldner; G F Cahill
Journal: J Clin Invest Date: 1967-06 Impact factor: 14.808

7. Human C-peptide immunoreactivity (CPR) in blood and urine - evaluation of a radioimmunoassay method and its clinical applications.

Authors: T Kuzuya; T Saito; S Yoshida; A Matsuda
Journal: Diabetologia Date: 1976-10 Impact factor: 10.122

8. Metabolism of proinsulin, insulin, and C-peptide in the rat.

Authors: A I Katz; A H Rubenstein
Journal: J Clin Invest Date: 1973-05 Impact factor: 14.808

8 in total

9 in total

1. The effect of exercise on the absorption of inhaled human insulin in healthy volunteers.

Authors: Astrid H Petersen; Gerd Köhler; Stefan Korsatko; Andrea Wutte; Manfred Wonisch; Agnes Mautner; Birgitte B Rønn; Per Clauson; Torben Laursen; Per Wollmer; Thomas R Pieber
Journal: Br J Clin Pharmacol Date: 2007-08-31 Impact factor: 4.335

2. Insulin absorption from the abdomen and the thigh in healthy subjects during rest and exercise: blood glucose, plasma insulin, growth hormone, adrenaline and noradrenaline levels.

Authors: H Süsstrunk; B Morell; W H Ziegler; E R Froesch
Journal: Diabetologia Date: 1982-03 Impact factor: 10.122

Disappearance rate of endogenous human C-peptide from blood.

1. Human C-peptide in normal and diabetic subjects.

2. Proinsulin, insulin, and C-peptide concentrations in human portal and peripheral blood.

3. Disappearance of immunoreactive insulin in normal and adult-onset diabetic subjects.

4. Significance of disappearance-rate of injected insulin.

5. Plasma insulin responses to glucose in femoral, hepatic, and pancreatic veins in dogs.

6. Diffusion of glucose, insulin, inulin, and Evans blue protein into thoracic duct lymph of man.

7. Human C-peptide immunoreactivity (CPR) in blood and urine - evaluation of a radioimmunoassay method and its clinical applications.

8. Metabolism of proinsulin, insulin, and C-peptide in the rat.

1. The effect of exercise on the absorption of inhaled human insulin in healthy volunteers.

2. Insulin absorption from the abdomen and the thigh in healthy subjects during rest and exercise: blood glucose, plasma insulin, growth hormone, adrenaline and noradrenaline levels.

3. Kinetics of human connecting peptide in normal and diabetic subjects.

4. The measurement and validation of the nonsteady-state rates of C-peptide appearance in the dog.

5. Reduced incretin effect in type 2 (non-insulin-dependent) diabetes.

6. Pancreatic endocrine response to the first feed in term newborn infants.

7. Abnormal proinsulin/C-peptide ratio in juvenile diabetes.

8. Can chewing gum be another source of preanalytical variability in fasting outpatients?

9. Biological activity versus physiological function of proinsulin C-peptide.