| Literature DB >> 9766221 |
B Beall1.
Abstract
Two iron-regulated genes with deduced homology to TonB-dependent ferric siderophore receptors were cloned from Bordetella bronchiseptica by screening a library of TnphoA insertion mutants. bfrB and bfrC were iron-repressed in B. bronchiseptica by a Fur-dependent mechanism, and were expressed from promoters overlapped by potential Fur-binding sites. Both genes were highly conserved among Bordetella species and were also iron-regulated in Bordetella pertussis. bfrB and bfrC mutants of both species and a bfrB-bfrC double mutant of B. bronchiseptica had no discernible defects in utilization of known iron sources for Bordetella.Entities:
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Year: 1998 PMID: 9766221 DOI: 10.1016/s0923-2508(98)80079-x
Source DB: PubMed Journal: Res Microbiol ISSN: 0923-2508 Impact factor: 3.992