C D Hsu1, F R Witter. 1. Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, CT, USA.
Abstract
OBJECTIVE: The purpose of this study was to determine whether the incidence of urinary tract infections and postpartum endometritis were increased in preeclamptic pregnancies. METHOD: We conducted a retrospective study of 13852 pregnant women, using a perinatal database at The Johns Hopkins Hospital, over the past 5 years. The incidence of urinary tract infections and postpartum endometritis was analyzed using the chi-squared test and logistic regression analysis. Statistical significance was set at P < 0.05. RESULTS: There were 345 (2.5%) mild preeclamptics and 440 (3.2%) severe preeclamptics. The incidence of urinary tract infections and postpartum endometritis in preeclamptic patients was significantly higher than that in non-hypertensive pregnant patients. After controlling for confounding variables, severe preeclampsia was still found to be an independent significant risk factor for both urinary tract infections and postpartum endometritis. CONCLUSION: Our data show a significant increase in urogenital infection in preeclamptic pregnancy. This may reflect higher rates of underlying renal disease and placental bed abnormalities occurring in preeclampsia.
OBJECTIVE: The purpose of this study was to determine whether the incidence of urinary tract infections and postpartum endometritis were increased in preeclamptic pregnancies. METHOD: We conducted a retrospective study of 13852 pregnant women, using a perinatal database at The Johns Hopkins Hospital, over the past 5 years. The incidence of urinary tract infections and postpartum endometritis was analyzed using the chi-squared test and logistic regression analysis. Statistical significance was set at P < 0.05. RESULTS: There were 345 (2.5%) mild preeclamptics and 440 (3.2%) severe preeclamptics. The incidence of urinary tract infections and postpartum endometritis in preeclamptic patients was significantly higher than that in non-hypertensive pregnant patients. After controlling for confounding variables, severe preeclampsia was still found to be an independent significant risk factor for both urinary tract infections and postpartum endometritis. CONCLUSION: Our data show a significant increase in urogenital infection in preeclamptic pregnancy. This may reflect higher rates of underlying renal disease and placental bed abnormalities occurring in preeclampsia.
Authors: Catherine L Haggerty; Mark A Klebanoff; Inge Panum; Soren A Uldum; Debra C Bass; Jorn Olsen; James M Roberts; Roberta B Ness Journal: Pregnancy Hypertens Date: 2013-07-01 Impact factor: 2.899
Authors: Kaori Koga; Ingrid Cardenas; Paulomi Aldo; Vikki M Abrahams; Bing Peng; Sara Fill; Roberto Romero; Gil Mor Journal: Am J Reprod Immunol Date: 2009-03 Impact factor: 3.886