C A Brewer1, D Shevlin. 1. Department of Obstetrics and Gynecology, Southern Illinois University School of Medicine, and St. John's Hospital, Springfield 62794-1315, USA.
Abstract
BACKGROUND: Chemotherapy for steroid tumors of unspecified type has met with limited success and the overall prognosis has been poor. CASE: A patient with a virilizing steroid tumor, otherwise unspecified, with demonstrated progressive disease after surgical debulking. Treatment with multiagent chemotherapy failed, but the patient subsequently had a robust response to GnRH agonist therapy. CONCLUSION: GnRH analogue treatment should be considered prior to cytotoxic chemotherapy in cases of steroid tumor, not otherwise specified.
BACKGROUND: Chemotherapy for steroid tumors of unspecified type has met with limited success and the overall prognosis has been poor. CASE: A patient with a virilizing steroid tumor, otherwise unspecified, with demonstrated progressive disease after surgical debulking. Treatment with multiagent chemotherapy failed, but the patient subsequently had a robust response to GnRH agonist therapy. CONCLUSION:GnRH analogue treatment should be considered prior to cytotoxic chemotherapy in cases of steroid tumor, not otherwise specified.
Authors: Danuta Vasilevska; Vilius Rudaitis; Dominika Vasilevska; Ugnius Mickys; Sara Wawrysiuk; Andrzej Semczuk Journal: J Int Med Res Date: 2021-01 Impact factor: 1.671