| Literature DB >> 976442 |
N Papanicolaou, N Lefkos, M Safar, M Paris, J Bariety, M Milliez.
Abstract
Urinary prostaglandins (PGEs and PGFs), sodium and potassium were measured in 17 essentially hypertensive patients. Significant positive correlations were found between a) PGEs secreted in 24 h and sodium excreted in 24 h, b) the ratio PGEs/UnaV before and PGEs/UnaV after volume expansion and c) the ration Na/K and urinary PGEs. It was suggested that renal PGEs, potent natriuretic and diuretic substances, play an important homeostatic role in the extracellular fluid regulation, and consequently in long-term control of the arterial blood pressure.Entities:
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Year: 1976 PMID： 976442 DOI： 10.1007/BF01953093
Source DB: PubMed Journal: Experientia ISSN： 0014-4754