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Literature DB >> 976428

Elevated kidney glucosyltransferase activity in genetic prediabetic mice.

A S Reddi, W Oppermann, M P Reddy, C A Velasco, R A Camerini-Davalos.

Abstract

Glucosyltransferase activity in the renal cortex of genetic diabetic KK mice was significantly increased at 40 days of age when compared to that of Swiss albino and F1 hybrid mice. This increase in enzyme activity in the absence of glucose intolerance can be regarded as an earlier genetic marker for the diagnosis of diabetic microangiopathy.

Entities: Chemical Disease Species

Mesh：

Substances：
Glucosyltransferases

Year: 1976 PMID： 976428 DOI： 10.1007/BF01953068

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

14 in total

1. Determination of serum proteins by means of the biuret reaction.

Authors: A G GORNALL; C J BARDAWILL; M M DAVID
Journal: J Biol Chem Date: 1949-02 Impact factor: 5.157

Review 2. Insulin, growth hormone, and glucagon in prediabetes mellitus--a review.

Authors: K Johansen; J S Soeldner; R E Gleason
Journal: Metabolism Date: 1974-12 Impact factor: 8.694

3. Effect of genetic diabetes on kidney glucosyltransferase.

Authors: C Velasco; W Oppermann; N Marine; R A Camerini-Davalos
Journal: Horm Metab Res Date: 1974-09 Impact factor: 2.936

4. Glomerular changes in mice with spontaneous hereditary diabetes.

Authors: H Wehner; D Höhn; U Faix-Schade; H Huber; P Walzer
Journal: Lab Invest Date: 1972-09 Impact factor: 5.662

5. Excessive serum insulin response to oral glucose in obesity and mild diabetes. Study of 501 patients.

Authors: R Chiles; M Tzagournis
Journal: Diabetes Date: 1970-06 Impact factor: 9.461

6. Biochemical and ultrastructural studies of conjunctiva of hereditary diabetic mice.

Authors: P Kern; M Laurent; F Regnault
Journal: Rev Eur Etud Clin Biol Date: 1972-11

7. Platelet collagen adhesion characterization of collagen glucosyltransferase of plasma membranes of human blood platelets.

Authors: A J Barber; G A Jamieson
Journal: Biochim Biophys Acta Date: 1971-12-21

Elevated kidney glucosyltransferase activity in genetic prediabetic mice.

1. Determination of serum proteins by means of the biuret reaction.

Review 2. Insulin, growth hormone, and glucagon in prediabetes mellitus--a review.

3. Effect of genetic diabetes on kidney glucosyltransferase.

4. Glomerular changes in mice with spontaneous hereditary diabetes.

5. Excessive serum insulin response to oral glucose in obesity and mild diabetes. Study of 501 patients.

6. Biochemical and ultrastructural studies of conjunctiva of hereditary diabetic mice.

7. Platelet collagen adhesion characterization of collagen glucosyltransferase of plasma membranes of human blood platelets.

8. Studies of vascular and other lesions in KK mice.

9. Discordance of diabetic microangiopathy in identical twins.

10. Studies on the renal glomerular basement membrane. Preparation and chemical composition.

1. Circulating blood and platelets supply glycosyltransferases that enable extrinsic extracellular glycosylation.

2. Renal glucosyltransferase activity in highly-inbred spontaneously diabetic Chinese hamsters.

Review 3. [Diabetic glomerulosclerosis: current status of its morphology and pathogenesis (author's transl)].