Literature DB >> 9762944

Ovarian transposition by laparoscopy before radiotherapy in the treatment of Hodgkin's disease.

J M Classe1, M Mahé, P Moreau, M J Rapp, H Maisonneuve, A Lemevel, S Bourdin, J L Harousseau, J C Cuillière.   

Abstract

BACKGROUND: The use of inverted Y irradiation in the treatment of Hodgkin's disease with pelvic lymph node involvement can cause iatrogenic early menopause in young women as a result of ovarian exposure to radiation. Ovarian transposition protects the ovaries by removing them from the irradiation field. This surgical procedure, initially performed by laparotomy, can now be done by laparoscopy.
METHODS: During the period July 1994 to April 1996, laparoscopic ovarian transposition was performed on 4 young women with Hodgkin's disease 1 week before inverted Y radiotherapy. The surgical procedure, complications, length of hospitalization, and hormonal, clinical, and biologic results were evaluated.
RESULTS: The mean duration of hospitalization was 4 days, and there were no postoperative complications. Iatrogenic menopause did not occur in any of the patients during the mean follow-up period of 20.75 months (range, 6-35 months; median, 20 months).
CONCLUSIONS: Laparoscopy offers many advantages over laparotomy for ovarian transposition. This procedure, which can be performed without opening the abdominal wall, is highly efficient, requires only a short period of hospitalization, and leads to few postoperative complications. Laparoscopy is an attractive alternative to laparotomy for ovarian transposition in young women with advanced Hodgkin's disease who require pelvic radiotherapy.

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Year:  1998        PMID: 9762944

Source DB:  PubMed          Journal:  Cancer        ISSN: 0008-543X            Impact factor:   6.860


  2 in total

1.  Laparoscopic ovarian transposition to preserve ovarian function before pelvic radiation and chemotherapy in a young patient with rectal cancer.

Authors:  Leonard A Farber; John W Ames; Stephen Rush; David Gal
Journal:  MedGenMed       Date:  2005-03-17

Review 2.  Impact of radiotherapy on fertility, pregnancy, and neonatal outcomes in female cancer patients.

Authors:  Jennifer Y Wo; Akila N Viswanathan
Journal:  Int J Radiat Oncol Biol Phys       Date:  2009-04-01       Impact factor: 7.038

  2 in total

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