Literature DB >> 9762707

Role of enkephalinergic brain structures in regulating motivated behavior in rats with lesioned serotoninergic neurons.

N P Shugalev1.   

Abstract

The behavioral effects of injections of enkephalin into the substantia nigra or dorsal raphe nucleus were studied in rats with lesioned serotoninergic structures. Lesions were produced by intracerebral administration of the neurotoxin 5,7-dihydroxytryptamine. Treated rats showed normalization of conditioned drinking reflex extinction. It is proposed that there is a tight connection between the normalizing effects of enkephalin on rat behavior in conditions of deficient brain serotoninergic system function and increases in the efficiency of presynaptic inhibition of dopaminergic neurons.

Entities:  

Mesh：

Substances：

Year:  1998        PMID： 9762707     DOI： 10.1007/bf02464790

Source DB:  PubMed          Journal:  Neurosci Behav Physiol        ISSN： 0097-0549


  8 in total

1.  [The effect of serotonin and dopamine microinjections into the dorsal raphe nucleus on the extinction of a conditioned reflex in rats].

Authors:  N P Shugalev; G Hartmann
Journal:  Zh Vyssh Nerv Deiat Im I P Pavlova       Date:  1992 Mar-Apr       Impact factor: 0.437

2.  [Self-regulation of the dopaminergic neurons during extinction inhibition].

Authors:  N P Shugalev; G Hartman
Journal:  Zh Vyssh Nerv Deiat Im I P Pavlova       Date:  1989 Nov-Dec       Impact factor: 0.437

3.  [The behavioral effects of dopamine agonists in rats following the intrastriatal administration of 6-hydroxydopamine].

Authors:  N P Shugalëv; N G Iamshchikova; A V Stavrovskaia
Journal:  Fiziol Zh Im I M Sechenova       Date:  1994-01

4.  Facilitation of a dendritic calcium conductance by 5-hydroxytryptamine in the substantia nigra.

Authors:  S Nedergaard; J P Bolam; S A Greenfield
Journal:  Nature       Date:  1988-05-12       Impact factor: 49.962

5.  Differential effects of quinpirole in the nucleus accumbens depending on the initial level of locomotor activity.

Authors:  M Wu; S M Brudzynski; G J Mogenson
Journal:  Brain Res Bull       Date:  1993       Impact factor: 4.077

6.  Dopaminergic regulation of the serotonergic raphe-striatal pathway: microdialysis studies in freely moving rats.

Authors:  S Ferré; R Cortés; F Artigas
Journal:  J Neurosci       Date:  1994-08       Impact factor: 6.167

7.  Ascending dopaminergic projections from the dorsal raphe nucleus in the rat.

Authors:  T R Stratford; D Wirtshafter
Journal:  Brain Res       Date:  1990-03-12       Impact factor: 3.252

8.  Dopaminergic neurons of the substantia nigra modulate preproenkephalin A gene expression in rat striatal neurons.

Authors:  E Normand; T Popovici; B Onteniente; D Fellmann; D Piatier-Tonneau; C Auffray; B Bloch
Journal:  Brain Res       Date:  1988-01-26       Impact factor: 3.252
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.