Literature DB >> 9759383

[Scorpion toxins and defensins].

M Goyffon1, C Landon.   

Abstract

The scorpion venoms possess many neurotoxic peptides which constitute a group of molecular families with a common architecture and a high degree of polymorphism. This architecture is found also in circulating antimicrobial peptides belonging to the defensins family, which are especially structurally related to the blocking potassium channels neurotoxins. The diversification in functions with a unique architectural scheme is discussed taking in account the biophysiological characteristics of the scorpion order.

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Year:  1998        PMID: 9759383

Source DB:  PubMed          Journal:  C R Seances Soc Biol Fil        ISSN: 0037-9026


  4 in total

1.  Scorpion Potassium Channel-blocking Defensin Highlights a Functional Link with Neurotoxin.

Authors:  Lanxia Meng; Zili Xie; Qian Zhang; Yang Li; Fan Yang; Zongyun Chen; Wenxin Li; Zhijian Cao; Yingliang Wu
Journal:  J Biol Chem       Date:  2016-01-27       Impact factor: 5.157

Review 2.  Engineering venom's toxin-neutralizing antibody fragments and its therapeutic potential.

Authors:  Larissa M Alvarenga; Muhammad Zahid; Anne di Tommaso; Matthieu O Juste; Nicolas Aubrey; Philippe Billiald; Julien Muzard
Journal:  Toxins (Basel)       Date:  2014-08-21       Impact factor: 4.546

3.  AaeAP1 and AaeAP2: novel antimicrobial peptides from the venom of the scorpion, Androctonus aeneas: structural characterisation, molecular cloning of biosynthetic precursor-encoding cDNAs and engineering of analogues with enhanced antimicrobial and anticancer activities.

Authors:  Qiang Du; Xiaojuan Hou; Lei Wang; Yingqi Zhang; Xinping Xi; Hui Wang; Mei Zhou; Jinao Duan; Minjie Wei; Tianbao Chen; Chris Shaw
Journal:  Toxins (Basel)       Date:  2015-01-23       Impact factor: 4.546

4.  Assembling an arsenal, the scorpion way.

Authors:  Adi Kozminsky-Atias; Adi Bar-Shalom; Dan Mishmar; Noam Zilberberg
Journal:  BMC Evol Biol       Date:  2008-12-16       Impact factor: 3.260

  4 in total

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