| Literature DB >> 9757571 |
S Ono1, T Hirano, H Yasutake, T Matsumoto, I Yamaura, T Kato, H Morita, T Fujii, I Yamazaki, C Shimasaki, T Yoshimura.
Abstract
Six cyclic peptides with 5, 7, 9, 11, 13, and 15 amino acids, with the inhibitory sequence of the alpha-amylase inhibitor tendamistat, were synthesized. The 11-residue peptide inhibited porcine pancreatic alpha-amylase most potently (K1 0.29 +/- 0.09 microM). For the 11-residue peptide, the circular dichroism study suggested a preliminary relationship between its inhibitory activity and structural property.Entities:
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Year: 1998 PMID： 9757571 DOI： 10.1271/bbb.62.1621
Source DB: PubMed Journal: Biosci Biotechnol Biochem ISSN： 0916-8451 Impact factor: 2.043