Liver transplantation: problems and perspectives.

Orthotopic liver transplantation (OLT) has made remarkable advances. However, results vary according to the etiology and the severity of the liver disease. Shortage of donors is becoming an increasing problem because results are improving, more centers are embarking on transplantation and because the indications become wider. Measures have to be taken to improve the number of good donor livers and the condition of the recipient.