Literature DB >> 9755906

Correlating partitioning and caco-2 cell permeability of structurally diverse small molecular weight compounds.

M Yazdanian1, S L Glynn, J L Wright, A Hawi.   

Abstract

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Year:  1998        PMID： 9755906     DOI： 10.1023/a:1011930411574

Source DB:  PubMed          Journal:  Pharm Res        ISSN： 0724-8741            Impact factor:   4.200


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  16 in total

1.  Caco-2 cell monolayers as a model for drug transport across the intestinal mucosa.

Authors:  A R Hilgers; R A Conradi; P S Burton
Journal:  Pharm Res       Date:  1990-09       Impact factor: 4.200

Review 2.  Cell cultures as models for drug absorption across the intestinal mucosa.

Authors:  P Artursson
Journal:  Crit Rev Ther Drug Carrier Syst       Date:  1991       Impact factor: 4.889

3.  Correlation of drug absorption with molecular surface properties.

Authors:  K Palm; K Luthman; A L Ungell; G Strandlund; P Artursson
Journal:  J Pharm Sci       Date:  1996-01       Impact factor: 3.534

4.  Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells.

Authors:  P Artursson; J Karlsson
Journal:  Biochem Biophys Res Commun       Date:  1991-03-29       Impact factor: 3.575

5.  Drug delivery studies in Caco-2 monolayers. Synthesis, hydrolysis, and transport of O-cyclopropane carboxylic acid ester prodrugs of various beta-blocking agents.

Authors:  L Hovgaard; H Brøndsted; A Buur; H Bundgaard
Journal:  Pharm Res       Date:  1995-03       Impact factor: 4.200

6.  Comparison of the permeability characteristics of a human colonic epithelial (Caco-2) cell line to colon of rabbit, monkey, and dog intestine and human drug absorption.

Authors:  W Rubas; N Jezyk; G M Grass
Journal:  Pharm Res       Date:  1993-01       Impact factor: 4.200

7.  High lipophilicity decreases drug transport across intestinal epithelial cells.

Authors:  P Wils; A Warnery; V Phung-Ba; S Legrain; D Scherman
Journal:  J Pharmacol Exp Ther       Date:  1994-05       Impact factor: 4.030

8.  Comparison of intestinal permeabilities determined in multiple in vitro and in situ models: relationship to absorption in humans.

Authors:  B H Stewart; O H Chan; R H Lu; E L Reyner; H L Schmid; H W Hamilton; B A Steinbaugh; M D Taylor
Journal:  Pharm Res       Date:  1995-05       Impact factor: 4.200

9.  A correlation between the permeability characteristics of a series of peptides using an in vitro cell culture model (Caco-2) and those using an in situ perfused rat ileum model of the intestinal mucosa.

Authors:  D C Kim; P S Burton; R T Borchardt
Journal:  Pharm Res       Date:  1993-12       Impact factor: 4.200

10.  Molecular dynamics simulations of a lipid bilayer and of hexadecane: an investigation of membrane fluidity.

Authors:  R M Venable; Y Zhang; B J Hardy; R W Pastor
Journal:  Science       Date:  1993-10-08       Impact factor: 47.728
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  70 in total

1.  Mechanisms of transport and structure-permeability relationship of sulfasalazine and its analogs in Caco-2 cell monolayers.

Authors:  E Liang; J Proudfoot; M Yazdanian
Journal:  Pharm Res       Date:  2000-10       Impact factor: 4.200

2.  Comparison of human duodenum and Caco-2 gene expression profiles for 12,000 gene sequences tags and correlation with permeability of 26 drugs.

Authors:  Duxin Sun; Hans Lennernas; Lynda S Welage; Jeffery L Barnett; Christopher P Landowski; David Foster; David Fleisher; Kyung-Dall Lee; Gordon L Amidon
Journal:  Pharm Res       Date:  2002-10       Impact factor: 4.200

Review 3.  Microfabrication technologies for oral drug delivery.

Authors:  Shilpa Sant; Sarah L Tao; Omar Z Fisher; Qiaobing Xu; Nicholas A Peppas; Ali Khademhosseini
Journal:  Adv Drug Deliv Rev       Date:  2011-12-04       Impact factor: 15.470

4.  Prediction of drug transport through the blood-brain barrier in vivo: a comparison between two in vitro cell models.

Authors:  Stefan Lundquist; Mila Renftel; Julien Brillault; Laurence Fenart; Roméo Cecchelli; Marie-Pierre Dehouck
Journal:  Pharm Res       Date:  2002-07       Impact factor: 4.200

5.  Physicochemical properties and transport of steroids across Caco-2 cells.

Authors:  Fried Faassen; Jan Kelder; Johan Lenders; Rob Onderwater; Herman Vromans
Journal:  Pharm Res       Date:  2003-02       Impact factor: 4.200

6.  Quantitative biopharmaceutics classification system: the central role of dose/solubility ratio.

Authors:  Eleni Rinaki; Georgia Valsami; Panos Macheras
Journal:  Pharm Res       Date:  2003-12       Impact factor: 4.200

7.  The "high solubility" definition of the current FDA Guidance on Biopharmaceutical Classification System may be too strict for acidic drugs.

Authors:  Mehran Yazdanian; Katherine Briggs; Corinne Jankovsky; Amale Hawi
Journal:  Pharm Res       Date:  2004-02       Impact factor: 4.200

8.  Binding of novel fullerene inhibitors to HIV-1 protease: insight through molecular dynamics and molecular mechanics Poisson-Boltzmann surface area calculations.

Authors:  Haralambos Tzoupis; Georgios Leonis; Serdar Durdagi; Varnavas Mouchlis; Thomas Mavromoustakos; Manthos G Papadopoulos
Journal:  J Comput Aided Mol Des       Date:  2011-10-04       Impact factor: 3.686

Review 9.  Application of method suitability for drug permeability classification.

Authors:  Donna A Volpe
Journal:  AAPS J       Date:  2010-09-02       Impact factor: 4.009

10.  Real-time imaging and quantitative analysis of doxorubicin transport in a perfusable microvessel platform.

Authors:  Max I Bogorad; Peter C Searson
Journal:  Integr Biol (Camb)       Date:  2016-08-15       Impact factor: 2.192
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