Literature DB >> 9754640

cagA-positive Helicobacter pylori and risk for developing gastric carcinoma in Brazil.

D M Queiroz1, E N Mendes, G A Rocha, A M Oliveira, C A Oliveira, P P Magalhães, S B Moura, M M Cabral, A M Nogueira.   

Abstract

To evaluate a possible association between infection with cag A-positive strains and gastric carcinoma increased risk we studied 119 Helicobacter pylori-positive patients with gastric carcinoma and 119 matched controls. The presence of cag A gene was investigated by PCR in H. pylori isolates and in gastric biopsy specimens. A significant association was found between cag A-positive status and distal gastric carcinoma for both the intestinal and diffuse types of tumor for both males and females. On the other hand, no association was observed between cag A-positive status and proximal gastric carcinoma.

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Year:  1998        PMID： 9754640     DOI： 10.1002/(sici)1097-0215(19981005)78:2<135::aid-ijc1>3.0.co;2-#

Source DB:  PubMed          Journal:  Int J Cancer        ISSN： 0020-7136            Impact factor:   7.396


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