Literature DB >> 9748368

Symplostatin 1: A dolastatin 10 analogue from the marine cyanobacterium Symploca hydnoides.

G G Harrigan1, H Luesch, W Y Yoshida, R E Moore, D G Nagle, V J Paul, S L Mooberry, T H Corbett, F A Valeriote.   

Abstract

A new solid tumor selective cytotoxic analogue of dolastatin 10 (1) has been isolated from the marine cyanobacterium Symploca hydnoides, collected near Guam. This metabolite has been assigned the trivial name symplostatin 1 (2). This discovery supports the proposal that many compounds isolated from the seahare Dolabella auricularia, the original source of the dolastatins, are of dietary origin.

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Year:  1998        PMID： 9748368     DOI： 10.1021/np980321c

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  23 in total

Review 1.  Biological targets and mechanisms of action of natural products from marine cyanobacteria.

Authors:  Lilibeth A Salvador-Reyes; Hendrik Luesch
Journal:  Nat Prod Rep       Date:  2015-03       Impact factor: 13.423

Review 2.  Marine Mollusk-Derived Agents with Antiproliferative Activity as Promising Anticancer Agents to Overcome Chemotherapy Resistance.

Authors:  Maria Letizia Ciavatta; Florence Lefranc; Marianna Carbone; Ernesto Mollo; Margherita Gavagnin; Tania Betancourt; Ramesh Dasari; Alexander Kornienko; Robert Kiss
Journal:  Med Res Rev       Date:  2016-12-07       Impact factor: 12.944

Review 3.  Bioactive Compounds from Marine Heterobranchs.

Authors:  Conxita Avila; Carlos Angulo-Preckler
Journal:  Mar Drugs       Date:  2020-12-21       Impact factor: 5.118

4.  Targeted natural products discovery from marine cyanobacteria using combined phylogenetic and mass spectrometric evaluation.

Authors:  Lilibeth A Salvador-Reyes; Niclas Engene; Valerie J Paul; Hendrik Luesch
Journal:  J Nat Prod       Date:  2015-01-30       Impact factor: 4.050

5.  The carmaphycins: new proteasome inhibitors exhibiting an α,β-epoxyketone warhead from a marine cyanobacterium.

Authors:  Alban R Pereira; Andrew J Kale; Andrew T Fenley; Tara Byrum; Hosana M Debonsi; Michael K Gilson; Frederick A Valeriote; Bradley S Moore; William H Gerwick
Journal:  Chembiochem       Date:  2012-03-01       Impact factor: 3.164

6.  Veraguamides A-G, cyclic hexadepsipeptides from a dolastatin 16-producing cyanobacterium Symploca cf. hydnoides from Guam.

Authors:  Lilibeth A Salvador; Jason S Biggs; Valerie J Paul; Hendrik Luesch
Journal:  J Nat Prod       Date:  2011-03-29       Impact factor: 4.050

7.  Cyclic depsipeptides, grassypeptolides D and E and Ibu-epidemethoxylyngbyastatin 3, from a Red Sea Leptolyngbya cyanobacterium.

Authors:  Christopher C Thornburg; Muralidhara Thimmaiah; Lamiaa A Shaala; Andrew M Hau; Jay M Malmo; Jane E Ishmael; Diaa T A Youssef; Kerry L McPhail
Journal:  J Nat Prod       Date:  2011-08-01       Impact factor: 4.050

8.  Caldora penicillata gen. nov., comb. nov. (cyanobacteria), a pantropical marine species with biomedical relevance.

Authors:  Niclas Engene; Ana Tronholm; Lilibeth A Salvador-Reyes; Hendrik Luesch; Valerie J Paul
Journal:  J Phycol       Date:  2015-08       Impact factor: 2.923

9.  A direct pre-screen for marine bacteria producing compounds inhibiting quorum sensing reveals diverse planktonic bacteria that are bioactive.

Authors:  Jamie S Linthorne; Barbara J Chang; Gavin R Flematti; Emilio L Ghisalberti; David C Sutton
Journal:  Mar Biotechnol (NY)       Date:  2014-08-01       Impact factor: 3.619

10.  Morphological, chemical, and genetic diversity of tropical marine cyanobacteria Lyngbya spp. and Symploca spp. (Oscillatoriales).

Authors:  Robert W Thacker; Valerie J Paul
Journal:  Appl Environ Microbiol       Date:  2004-06       Impact factor: 4.792
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