Literature DB >> 9747472

Combined transfacial and neurosurgical approach to malignant tumours of the ethmoid sinus.

D Salvan1, M Julieron, P Marandas, F Janot, A M Leridant, C Domenge, G Mamelle, G Schwaab, B Luboinski.   

Abstract

In order to understand the risks and benefits of a combined transfacial and neurosurgical procedure for neoplasms of the ethmoid sinus, we reviewed all patients who underwent this surgical approach in our department between 1986 and 1994. The study included 41 patients. Pathological diagnoses included adenocarcinoma (31 patients), squamous cell carcinoma (three patients), aesthesioneuroblastoma (three patients), other (four patients). The overall morbidity rate was 39 per cent, and the post-operative mortality rate was 2.5 per cent. Complications were statistically more likely in patients with bone skull base reconstruction. The main carcinologic failures were local recurrences (24 per cent) and metastases (22 per cent). The one-year, three-year and five-year Kaplan Meir survival rates were respectively 84 per cent, 53 per cent and 36 per cent. In conclusion, the mortality and morbidity were acceptable, especially when no bone skull base reconstruction was performed. Better local control justifies a combined procedure with post-operative radiotherapy when tumours involve or reach the skull base.

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Year:  1998        PMID: 9747472     DOI: 10.1017/s0022215100140745

Source DB:  PubMed          Journal:  J Laryngol Otol        ISSN: 0022-2151            Impact factor:   1.469


  3 in total

1.  Craniofacial Resection for Sinonasal Malignant Tumors: Statistical Analysis of Surgical Outcome over 17 Years at a Single Institution.

Authors:  Seiichiro Mine; Naokatsu Saeki; Kentaro Horiguchi; Toyoyuki Hanazawa; Yoshitaka Okamoto
Journal:  Skull Base       Date:  2011-07

2.  Trans-Frontal Five-Fluorouracil (TraFFF): a novel technique for the application of adjuvant topical chemotherapeutic agents in sinonasal adenocarcinoma.

Authors:  Narinder Singh; Eugene Wong; Johnson Huang; Faruque Riffat
Journal:  BMJ Case Rep       Date:  2018-10-24

3.  Treatment Outcomes of Locally Advanced Squamous Cell Carcinoma of the Ethmoid Sinus Treated with Anterior Craniofacial Resection or Chemoradiotherapy.

Authors:  Takeharu Ono; Norimitsu Tanaka; Hirohito Umeno; Kiyohiko Sakata; Motohiro Morioka; Yoko Ohmaru; Hideaki Rikimaru; Noriyuki Koga; Kensuke Kiyokawa; Shun-Ichi Chitose; Buichiro Shin; Takeichiro Aso; Hidehiro Etoh; Toshi Abe
Journal:  Case Rep Oncol       Date:  2017-04-18
  3 in total

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