Literature DB >> 9746943

beta-Lactamases: protein evolution in real time.

J Petrosino1, C Cantu, T Palzkill.   

Abstract

The evolution and spread of bacteria resistant to beta-lactam antibiotics has progressed at an alarming rate. Bacteria may acquire resistance to a given drug by mutation of pre-existing genes or by the acquisition of new genes from other bacteria. One ongoing example of these mechanisms is the evolution of new variants of the TEM and SHV beta-lactamases with altered substrate specificity.

Entities:  

Mesh：

Substances：

Year:  1998        PMID： 9746943     DOI： 10.1016/s0966-842x(98)01317-1

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN： 0966-842X            Impact factor:   17.079


  33 in total

1.  Concentration-dependent selection of small phenotypic differences in TEM beta-lactamase-mediated antibiotic resistance.

Authors:  M C Negri; M Lipsitch; J Blázquez; B R Levin; F Baquero
Journal:  Antimicrob Agents Chemother       Date:  2000-09       Impact factor: 5.191

2.  Saturation mutagenesis of Asn152 reveals a substrate selectivity switch in P99 cephalosporinase.

Authors:  Scott T Lefurgy; René M de Jong; Virginia W Cornish
Journal:  Protein Sci       Date:  2007-12       Impact factor: 6.725

3.  Contribution of gene amplification to evolution of increased antibiotic resistance in Salmonella typhimurium.

Authors:  Song Sun; Otto G Berg; John R Roth; Dan I Andersson
Journal:  Genetics       Date:  2009-05-27       Impact factor: 4.562

4.  Influence of C-H...O interactions on the structural stability of β-lactamases.

Authors:  P Lavanya; Sudha Ramaiah; Anand Anbarasu
Journal:  J Biol Phys       Date:  2013-06-25       Impact factor: 1.365

Review 5.  Bacterial gene amplification: implications for the evolution of antibiotic resistance.

Authors:  Linus Sandegren; Dan I Andersson
Journal:  Nat Rev Microbiol       Date:  2009-08       Impact factor: 60.633

6.  R164H and V240H replacements by site-directed mutagenesis of TEM-149 extended-spectrum β-lactamase: kinetic analysis of TEM-149H240 and TEM-149H164-H240 laboratory mutants.

Authors:  Mariagrazia Perilli; Giuseppe Celenza; Paola Sandra Mercuri; Moreno Galleni; Cristina Pellegrini; Bernardetta Segatore; Gianfranco Amicosante
Journal:  Antimicrob Agents Chemother       Date:  2012-11-26       Impact factor: 5.191

Review 7.  Fragment-based inhibitor discovery against β-lactamase.

Authors:  Derek A Nichols; Adam R Renslo; Yu Chen
Journal:  Future Med Chem       Date:  2014-03       Impact factor: 3.808

8.  Kinetic study of the effect of histidines 240 and 164 on TEM-149 enzyme probed by β-lactam inhibitors.

Authors:  Mariagrazia Perilli; Alisia Mancini; Giuseppe Celenza; Carlo Bottoni; Pierangelo Bellio; Alessia Sabatini; Letizia Di Pietro; Fabrizia Brisdelli; Bernardetta Segatore; Gianfranco Amicosante
Journal:  Antimicrob Agents Chemother       Date:  2014-08-04       Impact factor: 5.191

9.  Fine mapping of the sequence requirements for binding of beta-lactamase inhibitory protein (BLIP) to TEM-1 beta-lactamase using a genetic screen for BLIP function.

Authors:  Ji Yuan; Wanzhi Huang; Dar-Chone Chow; Timothy Palzkill
Journal:  J Mol Biol       Date:  2009-04-21       Impact factor: 5.469

10.  Evolutionary trajectories of beta-lactamase CTX-M-1 cluster enzymes: predicting antibiotic resistance.

Authors:  Angela Novais; Iñaki Comas; Fernando Baquero; Rafael Cantón; Teresa M Coque; Andrés Moya; Fernando González-Candelas; Juan-Carlos Galán
Journal:  PLoS Pathog       Date:  2010-01-22       Impact factor: 6.823
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.