Literature DB >> 9745048

Direct visualisation of individual gene organisation in Trypanosoma brucei by high-resolution in situ hybridisation.

K Ersfeld1, K Asbeck, K Gull.   

Abstract

We achieved the direct visualisation of gene organisation in Trypanosoma brucei using fluorescent in situ hybridisation on extended nuclear DNA fibres. We demonstrated the repetitive nature of the tubulin gene cluster, which consists of up to 19 alpha- and beta-tubulin genes arranged in tandem repeats.

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Year:  1998        PMID： 9745048     DOI： 10.1007/s004120050302

Source DB:  PubMed          Journal:  Chromosoma        ISSN： 0009-5915            Impact factor:   4.316


  11 in total

1.  The frequency of gene targeting in Trypanosoma brucei is independent of target site copy number.

Authors:  Bill Wickstead; Klaus Ersfeld; Keith Gull
Journal:  Nucleic Acids Res       Date:  2003-07-15       Impact factor: 16.971

2.  A novel strategy to identify the location of necessary and sufficient cis-acting regulatory mRNA elements in trypanosomes.

Authors:  Helena Webb; Roisin Burns; Nicola Kimblin; Louise Ellis; Mark Carrington
Journal:  RNA       Date:  2005-05-31       Impact factor: 4.942

3.  Actively transcribing RNA polymerase II concentrates on spliced leader genes in the nucleus of Trypanosoma cruzi.

Authors:  Fernando de Macedo Dossin; Sergio Schenkman
Journal:  Eukaryot Cell       Date:  2005-05

4.  Inhibition of mRNA maturation in trypanosomes causes the formation of novel foci at the nuclear periphery containing cytoplasmic regulators of mRNA fate.

Authors:  Susanne Kramer; Aline Marnef; Nancy Standart; Mark Carrington
Journal:  J Cell Sci       Date:  2012-02-24       Impact factor: 5.285

Review 5.  How do trypanosomes change gene expression in response to the environment?

Authors:  Angela Schwede; Susanne Kramer; Mark Carrington
Journal:  Protoplasma       Date:  2011-05-20       Impact factor: 3.356

6.  Evolution of tubulin gene arrays in Trypanosomatid parasites: genomic restructuring in Leishmania.

Authors:  Andrew P Jackson; Sue Vaughan; Keith Gull
Journal:  BMC Genomics       Date:  2006-10-18       Impact factor: 3.969

7.  Functional insights from a surface antigen mRNA-bound proteome.

Authors:  Larissa Melo do Nascimento; Franziska Egler; Katharina Arnold; Nina Papavasiliou; Christine Clayton; Esteban Erben
Journal:  Elife       Date:  2021-03-30       Impact factor: 8.140

8.  Locus-specific control of DNA resection and suppression of subtelomeric VSG recombination by HAT3 in the African trypanosome.

Authors:  Lucy Glover; David Horn
Journal:  Nucleic Acids Res       Date:  2014-10-09       Impact factor: 16.971

9.  Codon choice directs constitutive mRNA levels in trypanosomes.

Authors:  Janaina de Freitas Nascimento; Steven Kelly; Jack Sunter; Mark Carrington
Journal:  Elife       Date:  2018-03-15       Impact factor: 8.140

10.  An Alternative Strategy for Trypanosome Survival in the Mammalian Bloodstream Revealed through Genome and Transcriptome Analysis of the Ubiquitous Bovine Parasite Trypanosoma (Megatrypanum) theileri.

Authors:  Steven Kelly; Alasdair Ivens; G Adam Mott; Ellis O'Neill; David Emms; Olivia Macleod; Paul Voorheis; Kevin Tyler; Matthew Clark; Jacqueline Matthews; Keith Matthews; Mark Carrington
Journal:  Genome Biol Evol       Date:  2017-08-01       Impact factor: 3.416
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