A Castelbuono1, N R Miller. 1. Neuro-Ophthalmology Unit, The Wilmer Eye Institute, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA.
Abstract
PURPOSE: To determine the frequency of remission in patients with essential blepharospasm and Meige syndrome. METHOD: Retrospective analysis of patients by means of questionnaire in an institutional setting. RESULTS: Among 238 patients diagnosed in a single institution as having essential blepharospasm or Meige syndrome, 27 (11.3%) claimed to be symptom free without curative surgery. The average time between onset and resolution in the patients who claimed remission was 4.85 years (range, 3 months to 22 years). Among these patients, the duration of remission averaged 6.33 years (range, 1 year to 14 years). CONCLUSION: Patients with essential blepharospasm or Meige syndrome have a small but definite potential for spontaneous remission of symptoms, particularly within the first 5 years after onset of symptoms.
PURPOSE: To determine the frequency of remission in patients with essential blepharospasm and Meige syndrome. METHOD: Retrospective analysis of patients by means of questionnaire in an institutional setting. RESULTS: Among 238 patients diagnosed in a single institution as having essential blepharospasm or Meige syndrome, 27 (11.3%) claimed to be symptom free without curative surgery. The average time between onset and resolution in the patients who claimed remission was 4.85 years (range, 3 months to 22 years). Among these patients, the duration of remission averaged 6.33 years (range, 1 year to 14 years). CONCLUSION:Patients with essential blepharospasm or Meige syndrome have a small but definite potential for spontaneous remission of symptoms, particularly within the first 5 years after onset of symptoms.
Authors: Laura M Scorr; Hyun Joo Cho; Gamze Kilic-Berkmen; J Lucas McKay; Mark Hallett; Christine Klein; Tobias Baumer; Brian D Berman; Jeanne S Feuerstein; Joel S Perlmutter; Alfredo Berardelli; Gina Ferrazzano; Aparna Wagle-Shukla; Irene A Malaty; Joseph Jankovic; Steven T Bellows; Richard L Barbano; Marie Vidailhet; Emmanuel Roze; Cecilia Bonnet; Abhimanyu Mahajan; Mark S LeDoux; Victor S C Fung; Florence C F Chang; Giovanni Defazio; Tomaso Ercoli; Stewart Factor; Ted Wojno; H A Jinnah Journal: Dystonia Date: 2022-05-16