Literature DB >> 9742207

Signalling through the leukotriene B4 receptor involves both alphai and alpha16, but not alphaq or alpha11 G-protein subunits.

R Gaudreau1, C Le Gouill, S Métaoui, S Lemire, J Stankovà, M Rola-Pleszczynski.   

Abstract

COS-7 cells transfected with the leukotriene (LT) B4 receptor (BLTR) cDNA were unable to produce LTB4-induced inositol phosphates (IPs) in spite of the presence of endogenous Galphai, Galphaq and Galpha11 proteins. Co-transfection of BLTR with Galpha16, however, resulted in high levels of IP production, which were 17-, 10- and 6-fold higher than with co-transfected Galpha11, Galphaq and Galpha14, respectively. Co-transfection of BLTR with phospholipase C (PLC) beta2, on the other hand, resulted in efficient IP production and co-transfection of BLTR with both Galpha16 and PLCbeta2 resulted in a greater than additive response.

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Year:  1998        PMID： 9742207      PMCID： PMC1219746          DOI： 10.1042/bj3350015

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  38 in total

1.  Specific expression of heterotrimeric G proteins G12 and G16 during human myeloid differentiation.

Authors:  S Tenailleau; I Corre; S Hermouet
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2.  Two Gq class G proteins are expressed in human keratinocytes.

Authors:  B M Rock; L Xin; J N Wilcox
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3.  A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis.

Authors:  T Yokomizo; T Izumi; K Chang; Y Takuwa; T Shimizu
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4.  Detection of multiple forms of Gi alpha in HL60 cells.

Authors:  P M Murphy; B Eide; P Goldsmith; M Brann; P Gierschik; A Spiegel; H L Malech
Journal:  FEBS Lett       Date:  1987-08-31       Impact factor: 4.124

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Authors:  T Andersson; W Schlegel; A Monod; K H Krause; O Stendahl; D P Lew
Journal:  Biochem J       Date:  1986-12-01       Impact factor: 3.857

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Authors:  J Shefcyk; R Yassin; M Volpi; T F Molski; P H Naccache; J J Munoz; E L Becker; M B Feinstein; R I Sha'afi
Journal:  Biochem Biophys Res Commun       Date:  1985-02-15       Impact factor: 3.575

7.  Transformation of arachidonic acid by rabbit polymorphonuclear leukocytes. Formation of a novel dihydroxyeicosatetraenoic acid.

Authors:  P Borgeat; B Samuelsson
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8.  Thyrotropin-releasing hormone rapidly activates the phosphodiester hydrolysis of polyphosphoinositides in GH3 pituitary cells. Evidence for the role of a polyphosphoinositide-specific phospholipase C in hormone action.

Authors:  T F Martin
Journal:  J Biol Chem       Date:  1983-12-25       Impact factor: 5.157

9.  Effect of leukotriene B4, prostaglandin E2 and arachidonic acid on cytosolic-free calcium in human neutrophils.

Authors:  P D Lew; J M Dayer; C B Wollheim; T Pozzan
Journal:  FEBS Lett       Date:  1984-01-23       Impact factor: 4.124

10.  Pertussis toxin inhibition of chemotactic factor-induced calcium mobilization and function in human polymorphonuclear leukocytes.

Authors:  D W Goldman; F H Chang; L A Gifford; E J Goetzl; H R Bourne
Journal:  J Exp Med       Date:  1985-07-01       Impact factor: 14.307
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  7 in total

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3.  cDNA cloning and characterization of guinea-pig leukotriene B4 receptor.

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4.  Expression of functional leukotriene B4 receptors on human airway smooth muscle cells.

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5.  Structural insights on ligand recognition at the human leukotriene B4 receptor 1.

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Journal:  Nat Commun       Date:  2021-05-20       Impact factor: 14.919

6.  A second leukotriene B(4) receptor, BLT2. A new therapeutic target in inflammation and immunological disorders.

Authors:  T Yokomizo; K Kato; K Terawaki; T Izumi; T Shimizu
Journal:  J Exp Med       Date:  2000-08-07       Impact factor: 14.307

7.  Differential Contribution of BLT1 and BLT2 to Leukotriene B4-Induced Human NK Cell Cytotoxicity and Migration.

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  7 in total

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