Literature DB >> 9741917

Controlled chemical modification of hyaluronic acid: synthesis, applications, and biodegradation of hydrazide derivatives.

G D Prestwich1, D M Marecak, J F Marecek, K P Vercruysse, M R Ziebell.   

Abstract

Controlled modification of the carboxylic acid moieties of hyaluronic acid with mono- and polyfunctional hydrazides leads to biochemical probes, biopolymers with altered physical and chemical properties, tethered drugs for controlled release, and crosslinked hydrogels as biocompatible scaffoldings for tissue engineering. Methods for polyhydrazide synthesis, for prodrug preparation, for hydrogel crosslinking, and for monitoring biodegradation are described.

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Year:  1998        PMID: 9741917     DOI: 10.1016/s0168-3659(97)00242-3

Source DB:  PubMed          Journal:  J Control Release        ISSN: 0168-3659            Impact factor:   9.776


  53 in total

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7.  Hyaluronic acid depolymerization by ascorbate-redox effects on solid state cultivation of Streptococcus zooepidemicus in cashew apple fruit bagasse.

Authors:  André Casimiro de Macedo; Maria Helena Andrade Santana
Journal:  World J Microbiol Biotechnol       Date:  2012-03-02       Impact factor: 3.312

8.  Hyaluronic acid-based hydrogels containing covalently integrated drug depots: implication for controlling inflammation in mechanically stressed tissues.

Authors:  Longxi Xiao; Zhixiang Tong; Yingchao Chen; Darrin J Pochan; Chandran R Sabanayagam; Xinqiao Jia
Journal:  Biomacromolecules       Date:  2013-10-23       Impact factor: 6.988

9.  Effect of the molecular weight of polyethylene glycol (PEG) on the properties of chitosan-PEG-poly(N-isopropylacrylamide) hydrogels.

Authors:  Guoming Sun; Xian-Zheng Zhang; Chih-Chang Chu
Journal:  J Mater Sci Mater Med       Date:  2008-03-18       Impact factor: 3.896

10.  Experimental and Clinical Efficacy of Two Hyaluronic Acid-based Compounds of Different Cross-Linkage and Composition in the Rejuvenation of the Skin.

Authors:  Tommaso Iannitti; Julio César Morales-Medina; Alessandro Coacci; Beniamino Palmieri
Journal:  Pharm Res       Date:  2014-06-25       Impact factor: 4.200

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