Literature DB >> 9739928

[Vulvar Crohn disease: 3 cases].

S Fenniche1, M Mokni, S Haouet, A Ben Osman.   

Abstract

BACKGROUND: Vulvar involvement in Crohn's disease is uncommon. The elementary lesion is usually an ulceration: 44 cases have been reported in the literature. In 20 p. 100 of the cases, vulvar involvement is the only manifestation of the disease. We report 3 new cases of vulvar lesions in Crohn's disease. CASE REPORTS: The first case had vulvar lesions which complicated ileocolic Crohn's disease, in the other two cases there were no digestive manifestations. One patient developed voluminous edema of the right labium. The diagnosis of Crohn's disease of the vulva was suggested by the characteristic lesions, presence of epithelioid and giant cell granuloma at histology examination of the vulva specimen and finally on rapidly favorable course after treatment with sulfasalazine. The ulcers regressed with medical treatment but remission was temporary with recurrence at treatment withdrawal. DISCUSSION: These cases underline the difficulties encountered in establishing the diagnosis of Crohn's disease in patients who develop vulvar ulcerations alone with no signs of digestive disease and emphasize the difficult problem of long-term control.

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Year:  1997        PMID: 9739928

Source DB:  PubMed          Journal:  Ann Dermatol Venereol        ISSN: 0151-9638            Impact factor:   0.777


  2 in total

1.  Lymphoedema Vulva.

Authors:  A K Patra; A L Das; P Ramadasan
Journal:  Med J Armed Forces India       Date:  2011-07-21

2.  Metastatic Vulvar Crohn's Disease-A Rare Case Report and Short Review of Literature.

Authors:  Debajit Das; Bhaskar Gupta; Mahimanjan Saha
Journal:  Indian J Dermatol       Date:  2016 Jan-Feb       Impact factor: 1.494

  2 in total

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