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Literature DB >> 973985

A radioimmunoassay method for prednisolone: comparison with the competitive protein binding method.

J Chakraborty, J English, V Marks, M C Dumasia, D J Chapman.

Abstract

Cross reactivity of prednisolone with an antiserum raised against dexamethasone-21-hemisuccinate conjugated with bovine serum albumin was utilized to develop a radioimmunoassay for prednisolone in unextracted plasma. The results are in good agreement with those obtained with a standard competitive protein binding method employing prior extraction and separation of the synthetic from endogenous steroids.

Entities: Chemical Gene Species

Mesh：

Substances：
Prednisolone

Year: 1976 PMID： 973985 PMCID： PMC1428925 DOI： 10.1111/j.1365-2125.1976.tb00645.x

Source DB: PubMed Journal: Br J Clin Pharmacol ISSN： 0306-5251 Impact factor: 4.335

10 in total

1. Bioavailability and pharmacokinetics of prednisone in humans.

Authors: A R Disanto; K A Desante
Journal: J Pharm Sci Date: 1975-01 Impact factor: 3.534

2. Simultaneous competitive protein binding assay for cortissol, cortisone, and prednisolone in plasma, and its clinical application.

Authors: A K Turner; C J Carroll; J L Pinkus; D Charles; S C Chattoraj
Journal: Clin Chem Date: 1973-07 Impact factor: 8.327

3. Patterns of plasma levels of prednisolone after oral administration in man.

Authors: R Leclercq; G Copinschi
Journal: J Pharmacokinet Biopharm Date: 1974-04

4. Measurement of plasma prednisolone by a competitive protein-binding assay.

Authors: D H Sandberg; C Z Bacallao; W W Cleveland
Journal: Biochem Med Date: 1970-12

5. Radioimmunoassay for prednisolone.

Authors: W A Colburn; R H Buller
Journal: Steroids Date: 1973-06 Impact factor: 2.668

6. Decreased clearance of prednisolone, a factor in the development of corticosteroid side effects.

Authors: M Kozower; L Veatch; M M Kaplan
Journal: J Clin Endocrinol Metab Date: 1974-03 Impact factor: 5.958

7. Single-antibody technique for radioimmunoassay of cortisol in unextracted serum or plasma.

Authors: L B Foster; R T Dunn
Journal: Clin Chem Date: 1974-03 Impact factor: 8.327

8. Prednisolone levels in the plasma and urine: a study of two preparations in man.

Authors: J English; J Chakraborty; V Marks; D J Trigger; A G Thomson
Journal: Br J Clin Pharmacol Date: 1975-08 Impact factor: 4.335

9. Production and properties of antisera to dexamethasone-protein conjugates.

Authors: M C Dumasia; D I Chapman; M S Moss; C O'Connor
Journal: Biochem J Date: 1973-06 Impact factor: 3.857

10. Corticosteroids in liver disease: studies on the biological conversion of prednisone to prednisolone and plasma protein binding.

Authors: L W Powell; E Axelsen
Journal: Gut Date: 1972-09 Impact factor: 23.059

10 in total

9 in total

1. Plasma prednisolone levels from enteric and non-enteric coated tablets estimated by an original technique.

Authors: P J Morrison; I D Bradbrook; H J Rogers
Journal: Br J Clin Pharmacol Date: 1977-10 Impact factor: 4.335

2. Prednisolone pharmacokinetics compared between night and day in asthmatic and normal subjects.

Authors: W A McAllister; D M Mitchell; J V Collins
Journal: Br J Clin Pharmacol Date: 1981-03 Impact factor: 4.335

Review 3. Pharmacokinetics and bioavailability of prednisone and prednisolone in healthy volunteers and patients: a review.

Authors: J G Gambertoglio; W J Amend; L Z Benet
Journal: J Pharmacokinet Biopharm Date: 1980-02