Literature DB >> 9739760

The pS2/TFF1 trefoil factor, from basic research to clinical applications.

S Ribieras1, C Tomasetto, M C Rio.   

Abstract

pS2/TFF1 trefoil factor is normally expressed in the stomach, and is found ectopically in gastrointestinal inflammatory disorders and in various carcinomas. It is involved in stomach ontogenesis and in the maintenance of the integrity of the mucosa, and may represent a pharmacological tool for prevention and healing of gastrointestinal ulcerations. In breast cancer, it can be used to select patients suitable for hormone therapy. pS2/TFF1 is a pleiotropic factor involved in mucin polymerization, cell motility, cell proliferation and/or differentiation, and possibly in the nervous system.

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Year:  1998        PMID： 9739760     DOI： 10.1016/s0304-419x(98)00016-x

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  33 in total

1.  The human trefoil peptide, TFF1, is present in different molecular forms that are intimately associated with mucus in normal stomach.

Authors:  J L Newton; A Allen; B R Westley; F E May
Journal:  Gut       Date:  2000-03       Impact factor: 23.059

2.  High expression of the trefoil protein TFF1 in interval breast cancers.

Authors:  M Crosier; D Scott; R G Wilson; C D Griffiths; F E May; B R Westley
Journal:  Am J Pathol       Date:  2001-07       Impact factor: 4.307

3.  Loss of TFF1 is associated with activation of NF-κB-mediated inflammation and gastric neoplasia in mice and humans.

Authors:  Mohammed Soutto; Abbes Belkhiri; M Blanca Piazuelo; Barbara G Schneider; Dunfa Peng; Aixiang Jiang; M Kay Washington; Yasin Kokoye; Sheila E Crowe; Alexander Zaika; Pelayo Correa; Richard M Peek; Wael El-Rifai
Journal:  J Clin Invest       Date:  2011-04-01       Impact factor: 14.808

4.  Amplification and invasiveness of epithelial progenitors during gastric carcinogenesis in trefoil factor 1 knockout mice.

Authors:  S M Karam; C Tomasetto; M-C Rio
Journal:  Cell Prolif       Date:  2008-12       Impact factor: 6.831

5.  Identification of human urinary trefoil factor 1 as a novel calcium oxalate crystal growth inhibitor.

Authors:  Somchai Chutipongtanate; Yasushi Nakagawa; Suchai Sritippayawan; Jeeraporn Pittayamateekul; Paisal Parichatikanond; Bruce R Westley; Felicity E B May; Prida Malasit; Visith Thongboonkerd
Journal:  J Clin Invest       Date:  2005-11-23       Impact factor: 14.808

6.  Gastrointestinal tract specific gene GDDR inhibits the progression of gastric cancer in a TFF1 dependent manner.

Authors:  Guanghui Chu; Shengbin Qi; Guodong Yang; Kefeng Dou; Jianjun Du; Zifan Lu
Journal:  Mol Cell Biochem       Date:  2011-08-26       Impact factor: 3.396

7.  Molecular forms of trefoil factor 1 in normal gastric mucosa and its expression in normal and abnormal gastric tissues.

Authors:  Jian-Lin Ren; Jin-Yan Luo; Ya-Pi Lu; Lin Wang; Hua-Xiu Shi
Journal:  World J Gastroenterol       Date:  2006-12-07       Impact factor: 5.742

8.  Comparison of serum trefoil factor 3 with the pepsinogen test for the screening of diffuse-type gastric cancer.

Authors:  Ju Yup Lee; Kyung Sik Park; Hyun-Gyo Lee; Won-Ki Baek; Kwang Bum Cho; Yoo Jin Lee; Yoon Suk Lee; Seung-Wan Ryu
Journal:  Clin Exp Med       Date:  2016-05-06       Impact factor: 3.984

9.  Prognostic Value of Trefoil Factor 3 Expression in Patients with Gastric Cancer.

Authors:  Yoshiki Taniguchi; Yukinori Kurokawa; Tsuyoshi Takahashi; Jota Mikami; Yasuhiro Miyazaki; Koji Tanaka; Tomoki Makino; Makoto Yamasaki; Kiyokazu Nakajima; Masaki Mori; Yuichiro Doki
Journal:  World J Surg       Date:  2018-12       Impact factor: 3.352

10.  Airway trefoil factor expression during naphthalene injury and repair.

Authors:  Melanie A Greeley; Laura S Van Winkle; Patricia C Edwards; Charles G Plopper
Journal:  Toxicol Sci       Date:  2009-10-30       Impact factor: 4.849
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