Literature DB >> 9737777

Negative association between asthma and variants of CC16(CC10) on chromosome 11q13 in British and Japanese populations.

P S Gao1, X Q Mao, M Kawai, T Enomoto, S Sasaki, O Tanabe, K Yoshimura, S R Shaldon, Y Dake, H Kitano, P Coull, T Shirakawa, J M Hopkin.   

Abstract

The gene encoding Clara cell-derived inflammatory molecule CC16 has been cited as a candidate gene for atopic asthma on chromosome 1lq13. A genetic association study was performed with variants of the CC16 gene on chromosome 1lq13 in relation to asthma in British (n=275) and Japanese (n=300) populations. No significant association was found between asthma and CC16 genotypes, irrespective of atopic status in these two populations. These data suggest that CC16 might not be the major locus for asthma on 11q13.

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Year:  1998        PMID: 9737777     DOI: 10.1007/s004390050783

Source DB:  PubMed          Journal:  Hum Genet        ISSN: 0340-6717            Impact factor:   4.132


  7 in total

1.  Association of an intragenic microsatellite marker in the CC16 gene with asthma in the Indian population.

Authors:  Shilpy Sharma; Balaram Ghosh
Journal:  J Hum Genet       Date:  2004-11-12       Impact factor: 3.172

Review 2.  Asthma from a pharmacogenomic point of view.

Authors:  C Szalai; I Ungvári; L Pelyhe; G Tölgyesi; A Falus
Journal:  Br J Pharmacol       Date:  2008-03-03       Impact factor: 8.739

3.  The Ile198Thr and Ala379Val variants of plasmatic PAF-acetylhydrolase impair catalytical activities and are associated with atopy and asthma.

Authors:  S Kruse; X Q Mao; A Heinzmann; S Blattmann; M H Roberts; S Braun; P S Gao; J Forster; J Kuehr; J M Hopkin; T Shirakawa; K A Deichmann
Journal:  Am J Hum Genet       Date:  2000-03-24       Impact factor: 11.025

4.  The CD14 C-159T polymorphism is not associated with asthma or asthma severity in an Australian adult population.

Authors:  M-A Kedda; F Lose; D Duffy; E Bell; P J Thompson; J Upham
Journal:  Thorax       Date:  2005-03       Impact factor: 9.139

5.  Association between asthma-related phenotypes and the CC16 A38G polymorphism in an unselected population of young adult Danes.

Authors:  Pierre V Candelaria; Vibeke Backer; Ingrid A Laing; Celeste Porsbjerg; Steen Nepper-Christensen; Nick de Klerk; Jack Goldblatt; Peter N Le Souëf
Journal:  Immunogenetics       Date:  2005-03-03       Impact factor: 2.846

Review 6.  Interactions between genes and environmental factors in asthma and atopy: new developments.

Authors:  Claudia Sengler; Susanne Lau; Ulrich Wahn; Renate Nickel
Journal:  Respir Res       Date:  2001-10-31

Review 7.  Association studies for asthma and atopic diseases: a comprehensive review of the literature.

Authors:  Sabine Hoffjan; Dan Nicolae; Carole Ober
Journal:  Respir Res       Date:  2003-12-04
  7 in total

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