Literature DB >> 9736582

Susceptibilities of Candida species isolated from the lower gastrointestinal tracts of high-risk patients to the new semisynthetic echinocandin LY303366 and other antifungal agents.

G G Zhanel1, J A Karlowsky, S A Zelenitsky, M A Turik, D J Hoban.   

Abstract

Fifty-two percent of stool specimens collected from 1,200 high-risk patients were colonized with yeasts, primarily Candida albicans (53. 6%) and Candida glabrata (35.7%). Susceptibilities to all antifungal agents tested, including LY303366, were similar to those reported previously for Candida species isolated from blood.

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Year:  1998        PMID： 9736582      PMCID： PMC105852     

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  5 in total

1.  Mechanisms of association of Candida albicans with intestinal mucosa.

Authors:  M J Kennedy; P A Volz; C A Edwards; R J Yancey
Journal:  J Med Microbiol       Date:  1987-12       Impact factor: 2.472

Review 2.  Candidemia in a Canadian tertiary care hospital from 1976 to 1996.

Authors:  J A Karlowsky; G G Zhanel; K A Klym; D J Hoban; A M Kabani
Journal:  Diagn Microbiol Infect Dis       Date:  1997-09       Impact factor: 2.803

3.  In vitro susceptibilities of clinical yeast isolates to a new echinocandin derivative, LY303366, and other antifungal agents.

Authors:  M A Pfaller; S A Messer; S Coffman
Journal:  Antimicrob Agents Chemother       Date:  1997-04       Impact factor: 5.191

4.  In vitro activity of a new semisynthetic echinocandin, LY-303366, against systemic isolates of Candida species, Cryptococcus neoformans, Blastomyces dermatitidis, and Aspergillus species.

Authors:  G G Zhanel; J A Karlowsky; G A Harding; T V Balko; S A Zelenitsky; M Friesen; A Kabani; M Turik; D J Hoban
Journal:  Antimicrob Agents Chemother       Date:  1997-04       Impact factor: 5.191

5.  Antifungal dynamics of LY 303366, an investigational echinocandin B analog, against Candida ssp.

Authors:  M E Ernst; M E Klepser; E J Wolfe; M A Pfaller
Journal:  Diagn Microbiol Infect Dis       Date:  1996 Nov-Dec       Impact factor: 2.803
  5 in total
  2 in total

1.  Toxicity of LY303366, an echinocandin antifungal, in mice pretreated with glucocorticoids.

Authors:  K V Clemons; R A Sobel; D A Stevens
Journal:  Antimicrob Agents Chemother       Date:  2000-02       Impact factor: 5.191

2.  In vitro activities of anidulafungin against more than 2,500 clinical isolates of Candida spp., including 315 isolates resistant to fluconazole.

Authors:  M A Pfaller; L Boyken; R J Hollis; S A Messer; S Tendolkar; D J Diekema
Journal:  J Clin Microbiol       Date:  2005-11       Impact factor: 5.948
  2 in total

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