Literature DB >> 9736578

Control of Candida albicans murine vaginitis by topical administration of polycarbophil-econazole complex.

E Ghelardi1, A Tavanti, A Lupetti, F Celandroni, E Boldrini, M Campa, S Senesi.   

Abstract

The complexation of econazole with the mucoadhesive polycarbophil was found to significantly improve the therapeutic benefit of the drug in the topical treatment of experimental vaginal candidiasis in mice, while no difference in the antimycotic activity exerted by econazole and polycarbophil-econazole could be detected in vitro.

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Year:  1998        PMID： 9736578      PMCID： PMC105848     

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  11 in total

1.  A microautomated dilution method for susceptibility testing with antifungal drugs.

Authors:  L Polonelli; G Morace
Journal:  Mycopathologia       Date:  1984-04-30       Impact factor: 2.574

Review 2.  Absorption from the vagina.

Authors:  D P Benziger; J Edelson
Journal:  Drug Metab Rev       Date:  1983       Impact factor: 4.518

3.  Possible mechanisms for the enhancement of rectal absorption of hydrophilic drugs and polypeptides by aqueous polyacrylic acid gel.

Authors:  K Morimoto; T Iwamoto; K Morisaka
Journal:  J Pharmacobiodyn       Date:  1987-02

4.  Improved ocular penetration of gentamicin by mucoadhesive polymer polycarbophil in the pigmented rabbit.

Authors:  C M Lehr; Y H Lee; V H Lee
Journal:  Invest Ophthalmol Vis Sci       Date:  1994-05       Impact factor: 4.799

5.  Effects of the mucoadhesive polymer polycarbophil on the intestinal absorption of a peptide drug in the rat.

Authors:  C M Lehr; J A Bouwstra; W Kok; A G De Boer; J J Tukker; J C Verhoef; D D Breimer; H E Junginger
Journal:  J Pharm Pharmacol       Date:  1992-05       Impact factor: 3.765

6.  Quantification of vaginal Candida albicans infections in rodents.

Authors:  J F Ryley; S McGregor
Journal:  J Med Vet Mycol       Date:  1986-12

7.  Candida-specific cell-mediated immunity is demonstrable in mice with experimental vaginal candidiasis.

Authors:  P L Fidel; M E Lynch; J D Sobel
Journal:  Infect Immun       Date:  1993-05       Impact factor: 3.441

8.  Control of Candida albicans vaginitis in mice by short-duration butoconazole treatment in situ.

Authors:  A Valentin; C Bernard; M Mallié; M Huerre; J M Bastide
Journal:  Mycoses       Date:  1993 Nov-Dec       Impact factor: 4.377

9.  Evolution and replacement of Candida albicans strains during recurrent vaginitis demonstrated by DNA fingerprinting.

Authors:  K Schröppel; M Rotman; R Galask; K Mac; D R Soll
Journal:  J Clin Microbiol       Date:  1994-11       Impact factor: 5.948

10.  Switching of Candida albicans during successive episodes of recurrent vaginitis.

Authors:  D R Soll; R Galask; S Isley; T V Rao; D Stone; J Hicks; J Schmid; K Mac; C Hanna
Journal:  J Clin Microbiol       Date:  1989-04       Impact factor: 5.948
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  3 in total

1.  Antifungal activities of two new azasordarins, GW471552 and GW471558, in experimental models of oral and vulvovaginal candidiasis in immunosuppressed rats.

Authors:  A Martinez; S Ferrer; I Santos; E Jimenez; J Sparrowe; J Regadera; F G De Las Heras; D Gargallo-Viola
Journal:  Antimicrob Agents Chemother       Date:  2001-12       Impact factor: 5.191

2.  A novel itraconazole bioadhesive film for vaginal delivery: design, optimization, and physicodynamic characterization.

Authors:  Nitin B Dobaria; A C Badhan; R C Mashru
Journal:  AAPS PharmSciTech       Date:  2009-07-24       Impact factor: 3.246

3.  Role of chitosan on controlling the characteristics and antifungal activity of bioadhesive fluconazole vaginal tablets.

Authors:  Rawan A Fitaihi; Fadilah S Aleanizy; Samar Elsamaligy; Hanaa A Mahmoud; Mohsen A Bayomi
Journal:  Saudi Pharm J       Date:  2017-12-23       Impact factor: 4.330
  3 in total

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