Literature DB >> 9734762

Osteoarthritis and synovitis as major pathoses of the temporomandibular joint: comparison of clinical diagnosis with arthroscopic morphology.

H A Israel1, B Diamond, F Saed-Nejad, A Ratcliffe.   

Abstract

PURPOSE: The purposes of this investigation were to determine how common osteoarthritis and synovitis are in patients with severe, recalcitrant temporomandibular joint (TMJ) symptoms using clinical diagnostic criteria as well as arthroscopic examination, and to compare the accuracy of the clinical and arthroscopic diagnoses with respect to specificity and sensitivity. PATIENTS AND METHODS: Clinical and arthroscopic diagnoses were established in 126 joints of 84 patients with severe TMJ symptoms recalcitrant to conservative therapy. All joints were classified as having osteoarthritis (OA) or no osteoarthritis (non-OA) and synovitis (syn) or no synovitis (non-syn) using clinical and arthroscopic criteria. Chi-squared analysis was used to determine whether there was a relationship between the clinical and arthroscopic diagnoses. Preoperative clinical diagnoses were compared with arthroscopic morphologic diagnoses to determine the specificity and sensitivity of the clinical diagnostic criteria for synovitis and osteoarthritis.
RESULTS: A preoperative clinical diagnosis of OA was established in 59 of 126 joints (47%) compared with an arthroscopic diagnoses of OA in 82 of 126 joints (65%). Chi-squared analysis showed a significant relationship between the clinical and arthroscopic diagnosis of OA. A clinical diagnosis of OA was associated with a high specificity (.977); however, there were 23 of 82 (.293) false-negative findings and a sensitivity of only .707. A preoperative clinical diagnosis of synovitis was established in 114 of 126 joints (90%), compared with an arthroscopic diagnosis of synovitis in 112 of 126 (89%). Chi-squared analysis did not show a significant relationship between the clinical and arthroscopic diagnosis of synovitis. A clinical diagnosis of synovitis was associated with a high sensitivity (.920); however, there were 11 of 14 false-positive findings (.786) associated with a low specificity (.214).
CONCLUSIONS: Although there was high specificity for the clinical diagnosis of OA, the sensitivity was very low. (Comparison of clinical and arthroscopic diagnoses showed that osteoarthritis frequently escapes clinical detection. The clinical diagnosis of synovitis showed that low specificity and symptoms may be caused by other pathoses.

Entities:  

Mesh:

Year:  1998        PMID: 9734762     DOI: 10.1016/s0278-2391(98)90246-4

Source DB:  PubMed          Journal:  J Oral Maxillofac Surg        ISSN: 0278-2391            Impact factor:   1.895


  10 in total

1.  Association of radiographic and clinical findings in patients with temporomandibular joints osseous alteration.

Authors:  Raweewan Arayasantiparb; Somsak Mitrirattanakul; Panupol Kunasarapun; Harakun Chutimataewin; Pawares Netnoparat; Worapol Sae-Heng
Journal:  Clin Oral Investig       Date:  2019-05-11       Impact factor: 3.573

Review 2.  Interventions for the management of temporomandibular joint osteoarthritis.

Authors:  Raphael Freitas de Souza; Claudia H Lovato da Silva; Mona Nasser; Zbys Fedorowicz; Mohammed A Al-Muharraqi
Journal:  Cochrane Database Syst Rev       Date:  2012-04-18

Review 3.  Potential Role of Rebamipide in Osteoclast Differentiation and Mandibular Condylar Cartilage Homeostasis.

Authors:  Takashi Izawa; Islamy Rahma Hutami; Eiji Tanaka
Journal:  Curr Rheumatol Rev       Date:  2018-04-20

4.  Clinical factors affecting the outcome of arthocentesis.

Authors:  Syed Wakeel Andrabi; Altaf H Malik; Ajaz A Shah
Journal:  J Korean Assoc Oral Maxillofac Surg       Date:  2019-02-26

Review 5.  Osteoimmunology of Oral and Maxillofacial Diseases: Translational Applications Based on Biological Mechanisms.

Authors:  Carla Alvarez; Gustavo Monasterio; Franco Cavalla; Luis A Córdova; Marcela Hernández; Dominique Heymann; Gustavo P Garlet; Timo Sorsa; Pirjo Pärnänen; Hsi-Ming Lee; Lorne M Golub; Rolando Vernal; Alpdogan Kantarci
Journal:  Front Immunol       Date:  2019-07-18       Impact factor: 8.786

6.  Identification of key genes and pathways associated with sex difference in osteoarthritis based on bioinformatics analysis.

Authors:  Junchang Xu; Zijian Yan; Guihua Wu; Yongling Zheng; Xiaolong Liao; Feng Zou
Journal:  J Musculoskelet Neuronal Interact       Date:  2022-09-01       Impact factor: 1.864

7.  Progression of cartilage degradation, bone resorption and pain in rat temporomandibular joint osteoarthritis induced by injection of iodoacetate.

Authors:  Xue-Dong Wang; Xiao-Xing Kou; Dan-Qing He; Min-Min Zeng; Zhen Meng; Rui-Yun Bi; Yan Liu; Jie-Ni Zhang; Ye-Hua Gan; Yan-Heng Zhou
Journal:  PLoS One       Date:  2012-09-11       Impact factor: 3.240

8.  Gene Expression Profiling of IL-17A-Treated Synovial Fibroblasts from the Human Temporomandibular Joint.

Authors:  Toshio Hattori; Naomi Ogura; Miwa Akutsu; Mutsumi Kawashima; Suguru Watanabe; Ko Ito; Toshirou Kondoh
Journal:  Mediators Inflamm       Date:  2015-12-29       Impact factor: 4.711

9.  Injecting vascular endothelial growth factor into the temporomandibular joint induces osteoarthritis in mice.

Authors:  Pei Shen; ZiXian Jiao; Ji Si Zheng; Wei Feng Xu; Shang Yong Zhang; An Qin; Chi Yang
Journal:  Sci Rep       Date:  2015-11-04       Impact factor: 4.379

10.  Identification of Key Genes and Pathways Associated with Sex Differences in Osteoarthritis Based on Bioinformatics Analysis.

Authors:  Shiying Wang; Huanmei Wang; Wei Liu; Biaofang Wei
Journal:  Biomed Res Int       Date:  2019-12-06       Impact factor: 3.411

  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.