BACKGROUND: Deep venous thrombosis (DVT) is a common problem with potentially devastating results in patients undergoing major surgical procedures. Certain renal transplant recipients are particularly at risk for allograft loss as a consequence of renal vein and artery thrombosis. Over the past few years, low molecular weight heparin has been well established as an accepted modality of treatment and prophylaxis of DVT. The efficacy and safety of low molecular weight heparin in the prophylaxis of DVT following renal transplantation in adults has not previously been reported. METHODS: Dalteparin was administered to 120 adult renal transplant recipients postoperatively at the Oregon Health Sciences University. RESULTS: No patient developed allograft arterial or venous thrombosis. One patient developed subclavian vein thrombosis. No bleeding complications were encountered, and side effects were very minimal. CONCLUSION: Prophylaxis with dalteparin is an effective and safe modality for the prevention of thrombosis in adult patients undergoing renal transplantation.
BACKGROUND: Deep venous thrombosis (DVT) is a common problem with potentially devastating results in patients undergoing major surgical procedures. Certain renal transplant recipients are particularly at risk for allograft loss as a consequence of renal vein and artery thrombosis. Over the past few years, low molecular weight heparin has been well established as an accepted modality of treatment and prophylaxis of DVT. The efficacy and safety of low molecular weight heparin in the prophylaxis of DVT following renal transplantation in adults has not previously been reported. METHODS:Dalteparin was administered to 120 adult renal transplant recipients postoperatively at the Oregon Health Sciences University. RESULTS: No patient developed allograft arterial or venous thrombosis. One patient developed subclavian vein thrombosis. No bleeding complications were encountered, and side effects were very minimal. CONCLUSION: Prophylaxis with dalteparin is an effective and safe modality for the prevention of thrombosis in adult patients undergoing renal transplantation.
Authors: Rodrigo Guerra; Paulo Roberto Kawano; Marcelo Petean Amaro; Hamilto Akihissa Yamamoto; Fernando Ferreira Gomes Filho; João Luiz Amaro; Regina Paolucci El Dib; Herney Andres Garcia-Perdomo; Leonardo Oliveira Reis Journal: Am J Clin Exp Urol Date: 2022-06-15
Authors: Arvind Nagra; Richard S Trompeter; Oswald N Fernando; Geoff Koffman; John D Taylor; Rozanne Lord; Carol Hutchinson; Caoimhe O'Sullivan; Lesley Rees Journal: Pediatr Nephrol Date: 2004-03-12 Impact factor: 3.714
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Authors: Shady A Soliman; Ahmed A Shokeir; Ahmed S El-Hefnawy; Ahmed M Harraz; Mohamed M Kamal; Ahmed B Shehab El-Din; Mohamed A Ghoneim Journal: Arab J Urol Date: 2012-01-30
Authors: Shady A Soliman; Ahmed A Shokeir; Ahmed I Kamal; Ahmed S El-Hefnawy; Ahmed M Harraz; Mohamed M Kamal; Yasser Osman; Bedair Ali El-Dein; Ahmed B Shehab El-Dein; Mohamed A Ghoneim Journal: Arab J Urol Date: 2011-09-09