| Literature DB >> 9729714 |
Abstract
Within the past 18 months, common regulatory patterns have emerged among eukaryotic circadian systems--extending from fungi through to mammals. Heterodimeric complexes of PAS-domain-containing transcription factors play positive roles in clock-associated feedback loops, and classic clock proteins like FREQUENCY (FRQ), PERIOD (PER), and TIMELESS (TIM) appear as negative elements. Post-transcriptional control governs the amount and type of FRQ and makes the clock responsive to temperature.Entities:
Mesh:
Year: 1998 PMID: 9729714 DOI: 10.1016/s0959-437x(98)80109-3
Source DB: PubMed Journal: Curr Opin Genet Dev ISSN: 0959-437X Impact factor: 5.578