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Literature DB >> 9729502

Roles of Na-K-2Cl and Na-Cl cotransporters and ROMK potassium channels in urinary concentrating mechanism.

Abstract

The cloning of the apical transport proteins involved in NaCl absorption in the thick ascending limb of Henle and the distal convoluted tubule has ushered in a new era that promises to provide molecular details of the urinary concentrating and diluting processes. We now have at hand tools to examine the regulation of these proteins that can affect the concentrating and diluting capacity.

Entities: Chemical Gene

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Year: 1998 PMID： 9729502 DOI： 10.1152/ajprenal.1998.275.3.F325

Source DB: PubMed Journal: Am J Physiol ISSN： 0002-9513

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Cited

15 in total

1. K(+)-dependent gating of K(ir)1.1 channels is linked to pH gating through a conformational change in the pore.

Authors: U Schulte; S Weidemann; J Ludwig; J Ruppersberg; B Fakler
Journal: J Physiol Date: 2001-07-01 Impact factor: 5.182

Review 2. Molecular physiology of urinary concentration defect in elderly population.

Authors: B K Kishore; C M Kran; M Reif; A G Menon
Journal: Int Urol Nephrol Date: 2001 Impact factor: 2.370

Review 3. Use of knock-out mouse models for the study of renal ion channels.

Authors: H Barrière; M Tauc; P Poujeol
Journal: J Membr Biol Date: 2004-04-01 Impact factor: 1.843

4. High-throughput screening reveals a small-molecule inhibitor of the renal outer medullary potassium channel and Kir7.1.

Authors: L Michelle Lewis; Gautam Bhave; Brian A Chauder; Sreedatta Banerjee; Katharina A Lornsen; Rey Redha; Katherine Fallen; Craig W Lindsley; C David Weaver; Jerod S Denton
Journal: Mol Pharmacol Date: 2009-08-25 Impact factor: 4.436

10. Angiotensin II-induced hypertension increases plasma membrane Na pump activity by enhancing Na entry in rat thick ascending limbs.

Authors: Agustin Gonzalez-Vicente; Jeffrey L Garvin
Journal: Am J Physiol Renal Physiol Date: 2013-08-28

Roles of Na-K-2Cl and Na-Cl cotransporters and ROMK potassium channels in urinary concentrating mechanism.

1. K(+)-dependent gating of K(ir)1.1 channels is linked to pH gating through a conformational change in the pore.

Review 2. Molecular physiology of urinary concentration defect in elderly population.

Review 3. Use of knock-out mouse models for the study of renal ion channels.

4. High-throughput screening reveals a small-molecule inhibitor of the renal outer medullary potassium channel and Kir7.1.

5. pH gating of ROMK (K(ir)1.1) channels: control by an Arg-Lys-Arg triad disrupted in antenatal Bartter syndrome.

6. Race, sex, and the regulation of urine osmolality: observations made during water deprivation.

Review 7. Small-molecule modulators of inward rectifier K+ channels: recent advances and future possibilities.

8. Allelic-based gene-gene interaction associated with quantitative traits.

9. PGE2 inhibits basolateral 50 pS potassium channels in the thick ascending limb of the rat kidney.

10. Angiotensin II-induced hypertension increases plasma membrane Na pump activity by enhancing Na entry in rat thick ascending limbs.