Literature DB >> 9729408

The role of the complement system in traumatic brain injury.

P F Stahel1, M C Morganti-Kossmann, T Kossmann.   

Abstract

A traumatic impact to the brain induces an intracranial inflammatory response, which consequently leads to the development of brain edema and delayed neuronal death. Evidence from experimental, clinical, and in vitro studies highlight an important role for the complement system in contributing to inflammation within the injured brain. The present review summarizes the current understanding of the mechanisms of complement-mediated secondary brain injury after head trauma. Copyright 1998 Elsevier Science B.V.

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Year:  1998        PMID: 9729408     DOI: 10.1016/s0165-0173(98)00015-0

Source DB:  PubMed          Journal:  Brain Res Brain Res Rev


  40 in total

1.  Local and systemic pro-inflammatory and anti-inflammatory cytokine patterns in patients with chronic subdural hematoma: a prospective study.

Authors:  Milo Stanisic; Ansgar Oddne Aasen; Are Hugo Pripp; Karl-Fredrik Lindegaard; Jon Ramm-Pettersen; Staale Petter Lyngstadaas; Jugoslav Ivanovic; Ane Konglund; Eivind Ilstad; Tiril Sandell; Omar Ellingsen; Terje Sæhle
Journal:  Inflamm Res       Date:  2012-04-19       Impact factor: 4.575

Review 2.  A review of neuroprotection pharmacology and therapies in patients with acute traumatic brain injury.

Authors:  Kevin W McConeghy; Jimmi Hatton; Lindsey Hughes; Aaron M Cook
Journal:  CNS Drugs       Date:  2012-07-01       Impact factor: 5.749

3.  Targeted modulation of the neuroinflammatory response after spinal cord injury: the ongoing quest for the "holy grail".

Authors:  Philip F Stahel; Michael A Flierl
Journal:  Am J Pathol       Date:  2010-10-15       Impact factor: 4.307

Review 4.  Inhibition of complement as a therapeutic approach in inflammatory central nervous system (CNS) disease.

Authors:  S R Barnum
Journal:  Mol Med       Date:  1999-09       Impact factor: 6.354

Review 5.  [The relevance of the inflammatory response in the injured brain].

Authors:  O I Schmidt; I Leinhase; E Hasenboehler; S J Morgan; P F Stahel
Journal:  Orthopade       Date:  2007-03       Impact factor: 1.087

6.  Iron-induced necrotic brain cell death in rats with different aerobic capacity.

Authors:  Mingzhe Zheng; Hanjian Du; Wei Ni; Lauren G Koch; Steven L Britton; Richard F Keep; Guohua Xi; Ya Hua
Journal:  Transl Stroke Res       Date:  2015-02-05       Impact factor: 6.829

Review 7.  What has inflammation to do with traumatic brain injury?

Authors:  David Cederberg; Peter Siesjö
Journal:  Childs Nerv Syst       Date:  2009-11-26       Impact factor: 1.475

8.  Pharmacological inhibition of mannose-binding lectin ameliorates neurobehavioral dysfunction following experimental traumatic brain injury.

Authors:  Daiana De Blasio; Stefano Fumagalli; Luca Longhi; Franca Orsini; Alessandro Palmioli; Matteo Stravalaci; Gloria Vegliante; Elisa R Zanier; Anna Bernardi; Marco Gobbi; Maria-Grazia De Simoni
Journal:  J Cereb Blood Flow Metab       Date:  2016-07-20       Impact factor: 6.200

9.  Neurogenesis is required for behavioral recovery after injury in the visual system of Xenopus laevis.

Authors:  Caroline R McKeown; Pranav Sharma; Heidi E Sharipov; Wanhua Shen; Hollis T Cline
Journal:  J Comp Neurol       Date:  2013-07-01       Impact factor: 3.215

Review 10.  [Traumatic brain injury: impact on timing and modality of fracture care].

Authors:  P F Stahel; W Ertel; C E Heyde
Journal:  Orthopade       Date:  2005-09       Impact factor: 1.087

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