Literature DB >> 9727343

Analysis of 3D transient blood flow passing through an artificial aortic valve by Lattice-Boltzmann methods.

M Krafczyk1, M Cerrolaza, M Schulz, E Rank.   

Abstract

The development of flow instabilities due to high Reynolds number flow in artificial heart valve geometries inducing high strain rates and stresses often leads to hemolysis and related highly undesired effects. Geometric and functional optimization of artificial heart valves is therefore mandatory. In addition to experimental work in this field it is meanwhile possible to obtain increasing insight into flow dynamics by computer simulation of refined model problems. After giving an introductory overview we report the results of the simulation of three-dimensional transient physiological flows in fixed geometries similar to a CarboMedics bileaflet heart valve at different opening angles. The visualization of emerging complicated flow patterns gives detailed information about the transient history of the systems dynamical stability. Stress analysis indicates temporal shear stress peaks even far away from walls. The mathematical approach used is the Lattice Boltzmann method. We obtained reasonable results for velocity and shear stress fields. The code is implemented on parallel hardware in order to decrease computation time. Finally, we discuss problems, shortcomings and possible extensions of our approach.

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Year:  1998        PMID: 9727343     DOI: 10.1016/s0021-9290(98)00036-0

Source DB:  PubMed          Journal:  J Biomech        ISSN: 0021-9290            Impact factor:   2.712


  11 in total

1.  Acoustic driven flow and lattice Boltzmann simulations to study cell adhesion in biofunctionalized mu-fluidic channels with complex geometry.

Authors:  M A Fallah; V M Myles; T Krüger; K Sritharan; A Wixforth; F Varnik; S W Schneider; M F Schneider
Journal:  Biomicrofluidics       Date:  2010-05-19       Impact factor: 2.800

2.  Modeling the flow of dense suspensions of deformable particles in three dimensions.

Authors:  Michael M Dupin; Ian Halliday; Chris M Care; Lyuba Alboul; Lance L Munn
Journal:  Phys Rev E Stat Nonlin Soft Matter Phys       Date:  2007-06-27

3.  Computational phlebology: the simulation of a vein valve.

Authors:  Gavin A Buxton; Nigel Clarke
Journal:  J Biol Phys       Date:  2007-02-13       Impact factor: 1.365

Review 4.  Review of numerical methods for simulation of mechanical heart valves and the potential for blood clotting.

Authors:  Mohamad Shukri Zakaria; Farzad Ismail; Masaaki Tamagawa; Ahmad Fazli Abdul Aziz; Surjatin Wiriadidjaja; Adi Azrif Basri; Kamarul Arifin Ahmad
Journal:  Med Biol Eng Comput       Date:  2017-07-26       Impact factor: 2.602

5.  Device Thrombogenicity Emulator (DTE)--design optimization methodology for cardiovascular devices: a study in two bileaflet MHV designs.

Authors:  Michalis Xenos; Gaurav Girdhar; Yared Alemu; Jolyon Jesty; Marvin Slepian; Shmuel Einav; Danny Bluestein
Journal:  J Biomech       Date:  2010-05-21       Impact factor: 2.712

6.  Validation of a 3D computational fluid-structure interaction model simulating flow through an elastic aperture.

Authors:  A Quaini; S Canic; R Glowinski; S Igo; C J Hartley; W Zoghbi; S Little
Journal:  J Biomech       Date:  2011-12-03       Impact factor: 2.712

Review 7.  Towards non-thrombogenic performance of blood recirculating devices.

Authors:  D Bluestein; K B Chandran; K B Manning
Journal:  Ann Biomed Eng       Date:  2010-02-04       Impact factor: 3.934

8.  Device thrombogenicity emulation: a novel methodology for optimizing the thromboresistance of cardiovascular devices.

Authors:  Danny Bluestein; Gaurav Girdhar; Shmuel Einav; Marvin J Slepian
Journal:  J Biomech       Date:  2012-12-06       Impact factor: 2.712

9.  Integrated strategy for in vitro characterization of a bileaflet mechanical aortic valve.

Authors:  Francesca Maria Susin; Stefania Espa; Riccardo Toninato; Stefania Fortini; Giorgio Querzoli
Journal:  Biomed Eng Online       Date:  2017-02-16       Impact factor: 2.819

10.  MRI-based computational hemodynamics in patients with aortic coarctation using the lattice Boltzmann methods: Clinical validation study.

Authors:  Hanieh Mirzaee; Thomas Henn; Mathias J Krause; Leonid Goubergrits; Christian Schumann; Mathias Neugebauer; Titus Kuehne; Tobias Preusser; Anja Hennemuth
Journal:  J Magn Reson Imaging       Date:  2016-07-07       Impact factor: 4.813

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