Literature DB >> 9722999

Tubulin and FtsZ structures: functional and therapeutic implications.

A Desai1, T J Mitchison.   

Abstract

The microtubule cytoskeleton has lagged nearly a decade behind the actin cytoskeleton with respect to structural information on the basic polymer subunit. This structural inferiority complex has finally been lifted by two recent papers describing the structures of the alpha beta tubulin dimer and FtsZ, a protein similar to tubulin that is essential for cell division in prokaryotes.

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Year:  1998        PMID： 9722999     DOI： 10.1002/(SICI)1521-1878(199807)20:7<523::AID-BIES1>3.0.CO;2-L

Source DB:  PubMed          Journal:  Bioessays        ISSN： 0265-9247            Impact factor:   4.345


  3 in total

Review 1.  Tubulin depolymerization may be an ancient biological motor.

Authors:  J Richard McIntosh; Vladimir Volkov; Fazly I Ataullakhanov; Ekaterina L Grishchuk
Journal:  J Cell Sci       Date:  2010-10-15       Impact factor: 5.285

2.  Unveiling microbial activities along the halocline of Thetis, a deep-sea hypersaline anoxic basin.

Authors:  Maria G Pachiadaki; Michail M Yakimov; Violetta LaCono; Edward Leadbetter; Virginia Edgcomb
Journal:  ISME J       Date:  2014-06-20       Impact factor: 10.302

3.  Polyglycylation of tubulin is essential and affects cell motility and division in Tetrahymena thermophila.

Authors:  L Xia; B Hai; Y Gao; D Burnette; R Thazhath; J Duan; M H Bré; N Levilliers; M A Gorovsky; J Gaertig
Journal:  J Cell Biol       Date:  2000-05-29       Impact factor: 10.539
  3 in total

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