Literature DB >> 9722915

Genetic basis of abnormal B cell development.

M E Conley1, M D Cooper.   

Abstract

A susceptibility gene in the MHC class III region may underlie the defective B-cell differentiation in familial IgA deficiency and common variable immunodeficiency. Mutations in Bruton's tyrosine kinase, immunoglobulin heavy chain and lambda 5/14.1 surrogate light chain loci disrupt B-cell development to cause profound antibody deficiency. Mutational, biochemical and transgenic studies offer insight into the function of these and other 'antibody deficiency genes'.

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Year:  1998        PMID： 9722915     DOI： 10.1016/s0952-7915(98)80112-x

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN： 0952-7915            Impact factor:   7.486


  22 in total

1.  Posttranscriptional regulation of Bruton's tyrosine kinase expression in antigen receptor-stimulated splenic B cells.

Authors:  S Nisitani; A B Satterthwaite; K Akashi; I L Weissman; O N Witte; M I Wahl
Journal:  Proc Natl Acad Sci U S A       Date:  2000-03-14       Impact factor: 11.205

Review 2.  X-linked agammaglobulinemia.

Authors:  M E Conley; J Rohrer; Y Minegishi
Journal:  Clin Rev Allergy Immunol       Date:  2000-10       Impact factor: 8.667

3.  Genes required for B cell development.

Authors:  Mary Ellen Conley
Journal:  J Clin Invest       Date:  2003-12       Impact factor: 14.808

4.  Deletion of immunoglobulin beta in developing B cells leads to cell death.

Authors:  Eric Meffre; Michel C Nussenzweig
Journal:  Proc Natl Acad Sci U S A       Date:  2002-08-06       Impact factor: 11.205

Review 5.  Clinical consequences of defects in B-cell development.

Authors:  Andre M Vale; Harry W Schroeder
Journal:  J Allergy Clin Immunol       Date:  2010-04       Impact factor: 10.793

Review 6.  Flow Cytometry, a Versatile Tool for Diagnosis and Monitoring of Primary Immunodeficiencies.

Authors:  Roshini S Abraham; Geraldine Aubert
Journal:  Clin Vaccine Immunol       Date:  2016-04-04

Review 7.  Regulation of B lymphocyte development and activation by Bruton's tyrosine kinase.

Authors:  W N Khan
Journal:  Immunol Res       Date:  2001       Impact factor: 2.829

8.  Natural antibodies sustain differentiation and maturation of human dendritic cells.

Authors:  Jagadeesh Bayry; Sébastien Lacroix-Desmazes; Vladimira Donkova-Petrini; Cédric Carbonneil; Namita Misra; Yves Lepelletier; Sandrine Delignat; Sooryanarayana Varambally; Eric Oksenhendler; Yves Lévy; Marianne Debré; Michel D Kazatchkine; Olivier Hermine; Srini V Kaveri
Journal:  Proc Natl Acad Sci U S A       Date:  2004-09-20       Impact factor: 11.205

9.  The tec family tyrosine kinase Btk Regulates RANKL-induced osteoclast maturation.

Authors:  Seoung Hoon Lee; Taesoo Kim; Daewon Jeong; Nacksung Kim; Yongwon Choi
Journal:  J Biol Chem       Date:  2008-02-14       Impact factor: 5.157

Review 10.  B-lymphocyte tolerance and effector function in immunity and autoimmunity.

Authors:  Wasif N Khan; Jacqueline A Wright; Eden Kleiman; Justin C Boucher; Iris Castro; Emily S Clark
Journal:  Immunol Res       Date:  2013-12       Impact factor: 2.829
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