Literature DB >> 9722497

Aeruginosin 103-A, a thrombin inhibitor from the cyanobacterium Microcystis viridis.

S Kodani1, K Ishida, M Murakami.   

Abstract

Aeruginosin 103-A was isolated from the cultured freshwater cyanobacterium Microcystis viridis(NIES-103). Its structure was elucidated to be 1 on the basis of 2D NMR data. This linear peptide inhibited thrombin, with an IC50 of 9.0 microgram/mL.

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Year:  1998        PMID： 9722497     DOI： 10.1021/np980106w

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  8 in total

Review 1.  Chemodiversity in freshwater and terrestrial cyanobacteria - a source for drug discovery.

Authors:  George E Chlipala; Shunyan Mo; Jimmy Orjala
Journal:  Curr Drug Targets       Date:  2011-10       Impact factor: 3.465

2.  Synthesis of hydroxylated bicyclic amino acids from L-tyrosine: octahydro-1H-indole carboxylates.

Authors:  Joshua G Pierce; Dhanalakshmi Kasi; Makoto Fushimi; Anthony Cuzzupe; Peter Wipf
Journal:  J Org Chem       Date:  2008-09-04       Impact factor: 4.354

3.  Enantioselective syntheses and biological studies of aeruginosin 298-A and its analogs: application of catalytic asymmetric phase-transfer reaction.

Authors:  Yuhei Fukuta; Takashi Ohshima; Vijay Gnanadesikan; Tomoyuki Shibuguchi; Tetsuhiro Nemoto; Takaya Kisugi; Tatsufumi Okino; Masakatsu Shibasaki
Journal:  Proc Natl Acad Sci U S A       Date:  2004-03-02       Impact factor: 11.205

4.  Plasticity and evolution of aeruginosin biosynthesis in cyanobacteria.

Authors:  Keishi Ishida; Martin Welker; Guntram Christiansen; Sabrina Cadel-Six; Christiane Bouchier; Elke Dittmann; Christian Hertweck; Nicole Tandeau de Marsac
Journal:  Appl Environ Microbiol       Date:  2009-02-05       Impact factor: 4.792

5.  Investigation of the biosynthetic potential of endophytes in traditional Chinese anticancer herbs.

Authors:  Kristin I Miller; Chen Qing; Daniel Man Yuen Sze; Brett A Neilan
Journal:  PLoS One       Date:  2012-05-22       Impact factor: 3.240

6.  Biosynthesis and structure of aeruginoside 126A and 126B, cyanobacterial peptide glycosides bearing a 2-carboxy-6-hydroxyoctahydroindole moiety.

Authors:  Keishi Ishida; Guntram Christiansen; Wesley Y Yoshida; Rainer Kurmayer; Martin Welker; Nativitat Valls; Josep Bonjoch; Christian Hertweck; Thomas Börner; Thomas Hemscheidt; Elke Dittmann
Journal:  Chem Biol       Date:  2007-05

7.  Inhibitors of Serine Proteases from a Microcystis sp. Bloom Material Collected from Timurim Reservoir, Israel.

Authors:  Rawan Hasan-Amer; Shmuel Carmeli
Journal:  Mar Drugs       Date:  2017-12-01       Impact factor: 5.118

8.  FVIIa-sTF and Thrombin Inhibitory Activities of Compounds Isolated from Microcystis aeruginosa K-139.

Authors:  Andrea Roxanne J Anas; Akane Mori; Mineka Tone; Chiaki Naruse; Anna Nakajima; Hirohiko Asukabe; Yoshiaki Takaya; Susumu Y Imanishi; Tomoyasu Nishizawa; Makoto Shirai; Ken-Ichi Harada
Journal:  Mar Drugs       Date:  2017-08-30       Impact factor: 5.118
  8 in total

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