| Literature DB >> 9722485 |
L K Han1, H Ninomiya, M Taniguchi, K Baba, Y Kimura, H Okuda.
Abstract
An EtOAc-soluble fraction from a 80% Me2CO extract of the rhizomes of Astilbe thunbergii enhanced norepinephrine-induced lipolysis in rat fat cells, while an EtOAc-insoluble fraction had no effect. The active substances isolated from the EtOAc-soluble fraction of the rhizomes were identified as eucryphin (1), bergenin (2), and astilbin (3), which enhanced norepinephrine-induced lipolysis at concentrations of 10-1000 microgram/mL, while they themselves did not cause lipolysis. Furthermore, these compounds slightly stimulated adrenocorticotrophic hormone-induced lipolysis and inhibited insulin-induced lipogenesis from glucose.Entities:
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Year: 1998 PMID： 9722485 DOI： 10.1021/np980107o
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050