| Literature DB >> 9722480 |
P Magiatis1, E Melliou, A L Skaltsounis, S Mitaku, S Léonce, P Renard, A Pierré, G Atassi.
Abstract
The synthesis of known (3-6) and new (7-10 and 14-22) coumarins in the seselin and xanthyletin series is described. The cytotoxic activity of compounds 3-22 was carried out in vitro on L-1210 cells. The most active compounds were 9, 16, 18, and 20 in the seselin series and 10, 17, and 19 in the xanthyletin series. Structure-activity relationships are discussed.Entities:
Mesh：
Substances：
Year: 1998 PMID： 9722480 DOI： 10.1021/np9800295
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050