Literature DB >> 9722183

The GnRH promoter: target of transcription factors, hormones, and signaling pathways.

S B Nelson1, S A Eraly, P L Mellon.   

Abstract

Gonadotropin-releasing hormone (GnRH) is essential for normal reproductive maturation and function. We present a review of the known mechanisms of hypothalamic GnRH transcriptional control through the conserved GnRH promoter. Understanding this promoter region will allow us to comprehend better the complexities of the hypothalamic pituitary-gonadal axis.

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Year:  1998        PMID： 9722183     DOI： 10.1016/s0303-7207(98)00043-4

Source DB:  PubMed          Journal:  Mol Cell Endocrinol        ISSN： 0303-7207            Impact factor:   4.102


  11 in total

1.  Epigenetic changes coincide with in vitro primate GnRH neuronal maturation.

Authors:  Joseph R Kurian; Kim L Keen; Ei Terasawa
Journal:  Endocrinology       Date:  2010-09-22       Impact factor: 4.736

2.  Androgen receptor repression of gonadotropin-releasing hormone gene transcription via enhancer 1.

Authors:  Melissa J Brayman; Patricia A Pepa; Pamela L Mellon
Journal:  Mol Cell Endocrinol       Date:  2012-08-02       Impact factor: 4.102

3.  Regulation of gonadotropin-releasing hormone-1 gene transcription by members of the purine-rich element-binding protein family.

Authors:  Sheng Zhao; Robert J Kelm; Russell D Fernald
Journal:  Am J Physiol Endocrinol Metab       Date:  2009-12-08       Impact factor: 4.310

4.  Heterogeneous nuclear ribonucleoprotein A/B and G inhibits the transcription of gonadotropin-releasing-hormone 1.

Authors:  Sheng Zhao; Wayne J Korzan; Chun-Chun Chen; Russell D Fernald
Journal:  Mol Cell Neurosci       Date:  2007-08-29       Impact factor: 4.314

5.  Otx2 induction of the gonadotropin-releasing hormone promoter is modulated by direct interactions with Grg co-repressors.

Authors:  Rachel Larder; Pamela L Mellon
Journal:  J Biol Chem       Date:  2009-04-28       Impact factor: 5.157

6.  Neurokinin B causes acute GnRH secretion and repression of GnRH transcription in GT1-7 GnRH neurons.

Authors:  Christine A Glidewell-Kenney; Paul P Shao; Anita K Iyer; Anna M H Grove; Jason D Meadows; Pamela L Mellon
Journal:  Mol Endocrinol       Date:  2013-02-07

Review 7.  Molecular mechanisms of gonadotropin-releasing hormone signaling: integrating cyclic nucleotides into the network.

Authors:  Rebecca M Perrett; Craig A McArdle
Journal:  Front Endocrinol (Lausanne)       Date:  2013-11-20       Impact factor: 5.555

8.  Social Crowding during Development Causes Changes in GnRH1 DNA Methylation.

Authors:  Sebastian G Alvarado; Kapa Lenkov; Blake Williams; Russell D Fernald
Journal:  PLoS One       Date:  2015-10-30       Impact factor: 3.240

9.  R31C GNRH1 mutation and congenital hypogonadotropic hypogonadism.

Authors:  Luigi Maione; Frederique Albarel; Philippe Bouchard; Megan Gallant; Colleen A Flanagan; Regis Bobe; Joelle Cohen-Tannoudji; Rosario Pivonello; Annamaria Colao; Thierry Brue; Robert P Millar; Marc Lombes; Jacques Young; Anne Guiochon-Mantel; Jerome Bouligand
Journal:  PLoS One       Date:  2013-07-25       Impact factor: 3.240

Review 10.  Mathematical modeling of gonadotropin-releasing hormone signaling.

Authors:  Amitesh Pratap; Kathryn L Garner; Margaritis Voliotis; Krasimira Tsaneva-Atanasova; Craig A McArdle
Journal:  Mol Cell Endocrinol       Date:  2016-08-17       Impact factor: 4.102
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