Literature DB >> 9722045

Near fatal anticholinergic intoxication after routine fundoscopy.

G A Brunner1, S Fleck, T R Pieber, A Lueger, P Kaufmann, K H Smolle, H Brussee, G J Krejs.   

Abstract

We describe a case of severe anticholinergic intoxication following the topical instillation of tropicamide-containing eyedrops. Tropicamide is a short-acting atropine-like derivative and has been regarded as an effective and safe mydriatic. Half an hour after routine fundoscopy, a 62-year-old man experienced two generalized seizures with respiratory arrest and required intubation and mechanical ventilation. The patient was treated with physostigmine and made a full recovery.

Entities:  

Mesh:

Substances:

Year:  1998        PMID: 9722045     DOI: 10.1007/s001340050652

Source DB:  PubMed          Journal:  Intensive Care Med        ISSN: 0342-4642            Impact factor:   17.440


  6 in total

1.  Toxic effects of atropine and homatropine eyedrops in children.

Authors:  D HOEFNAGEL
Journal:  N Engl J Med       Date:  1961-01-26       Impact factor: 91.245

Review 2.  Initial management of ingestions of toxic substances.

Authors:  K Kulig
Journal:  N Engl J Med       Date:  1992-06-18       Impact factor: 91.245

3.  Reversal of central anticholinergic syndrome in man by physostigmine.

Authors:  R C Duvoisin; R Katz
Journal:  JAMA       Date:  1968-11-25       Impact factor: 56.272

4.  Anticholinergic delirium in a case of Munchausen syndrome.

Authors:  M H Hollender; R C Jamieson; E A McKee; H B Roback
Journal:  Am J Psychiatry       Date:  1978-11       Impact factor: 18.112

5.  Systemic absorption and anticholinergic activity of topically applied tropicamide.

Authors:  M L Vuori; T Kaila; E Iisalo; K M Saari
Journal:  J Ocul Pharmacol       Date:  1994

6.  Pupillary dilation with tropicamide 1% for funduscopic screening. A study of duration of action.

Authors:  W C Steinmann; M E Millstein; S H Sinclair
Journal:  Ann Intern Med       Date:  1987-08       Impact factor: 25.391

  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.