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Literature DB >> 9721319

Salmonella typhimurium nit is nadE: defective nitrogen utilization and ammonia-dependent NAD synthetase.

Abstract

S. typhimurium nit mutants are defective in nitrogen assimilation, despite having normal levels of assimilatory enzymes. Complementation, enzyme assays, and genetic mapping show that nit is nadE. We present evidence that ammonia, not glutamine, is the physiological substrate for eubacterial NAD synthetases and that low activity completely accounts for the mutant phenotype.

Entities: Chemical Disease Species

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Year: 1998 PMID： 9721319 PMCID： PMC107491

Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490

10 in total

1. Mutant strains (nit) of Salmonella typhimurium with a pleiotropic defect in nitrogen metabolism.

Authors: J Broach; C Neumann; S Kustu
Journal: J Bacteriol Date: 1976-10 Impact factor: 3.490

2. Construction of versatile low-copy-number vectors for cloning, sequencing and gene expression in Escherichia coli.

Authors: R F Wang; S R Kushner
Journal: Gene Date: 1991-04 Impact factor: 3.688

3. Complementation of nitrogen-regulatory (ntr-like) mutations in Rhodobacter capsulatus by an Escherichia coli gene: cloning and sequencing of the gene and characterization of the gene product.

Authors: P Allibert; J C Willison; P M Vignais
Journal: J Bacteriol Date: 1987-01 Impact factor: 3.490

4. Biosynthesis of diphosphopyridine nucleotide. The purification and the properties of diphospyridine nucleotide synthetase from Escherichia coli b.

Authors: R L Spencer; J Preiss
Journal: J Biol Chem Date: 1967-02-10 Impact factor: 5.157

Review 5. The amidotransferases.

Authors: H Zalkin
Journal: Adv Enzymol Relat Areas Mol Biol Date: 1993

6. Pathway and enzyme redundancy in putrescine catabolism in Escherichia coli.

Authors: Barbara L Schneider; Larry Reitzer
Journal: J Bacteriol Date: 2012-05-25 Impact factor: 3.490

7. The Escherichia coli efg gene and the Rhodobacter capsulatus adgA gene code for NH3-dependent NAD synthetase.

Authors: J C Willison; G Tissot
Journal: J Bacteriol Date: 1994-06 Impact factor: 3.490

8. Arginine catabolism and the arginine succinyltransferase pathway in Escherichia coli.

Authors: B L Schneider; A K Kiupakis; L J Reitzer
Journal: J Bacteriol Date: 1998-08 Impact factor: 3.490

9. Genetic characterization of the glutamate dehydrogenase gene (gdhA) of Salmonella typhimurium.

Authors: S A Rosenfeld; S M Dendinger; C H Murphy; J E Brenchley
Journal: J Bacteriol Date: 1982-05 Impact factor: 3.490

10. Structural gene for NAD synthetase in Salmonella typhimurium.

Authors: K T Hughes; B M Olivera; J R Roth
Journal: J Bacteriol Date: 1988-05 Impact factor: 3.490

10 in total

8 in total

Salmonella typhimurium nit is nadE: defective nitrogen utilization and ammonia-dependent NAD synthetase.

1. Mutant strains (nit) of Salmonella typhimurium with a pleiotropic defect in nitrogen metabolism.

2. Construction of versatile low-copy-number vectors for cloning, sequencing and gene expression in Escherichia coli.

3. Complementation of nitrogen-regulatory (ntr-like) mutations in Rhodobacter capsulatus by an Escherichia coli gene: cloning and sequencing of the gene and characterization of the gene product.

4. Biosynthesis of diphosphopyridine nucleotide. The purification and the properties of diphospyridine nucleotide synthetase from Escherichia coli b.

Review 5. The amidotransferases.

6. Pathway and enzyme redundancy in putrescine catabolism in Escherichia coli.

7. The Escherichia coli efg gene and the Rhodobacter capsulatus adgA gene code for NH3-dependent NAD synthetase.

8. Arginine catabolism and the arginine succinyltransferase pathway in Escherichia coli.

9. Genetic characterization of the glutamate dehydrogenase gene (gdhA) of Salmonella typhimurium.

10. Structural gene for NAD synthetase in Salmonella typhimurium.

Review 1. P(II) signal transduction proteins, pivotal players in microbial nitrogen control.

2. YrxA is the transcriptional regulator that represses de novo NAD biosynthesis in Bacillus subtilis.

3. Mechanism for coordinate regulation of rpoS by sRNA-sRNA interaction in Escherichia coli.

4. Genetics of nitrogen regulation in Methanococcus maripaludis.

5. The Crp-activated small noncoding regulatory RNA CyaR (RyeE) links nutritional status to group behavior.

6. Biogenesis and Homeostasis of Nicotinamide Adenine Dinucleotide Cofactor.

7. Glutamine versus ammonia utilization in the NAD synthetase family.

Review 8. Nitrogen assimilation in Escherichia coli: putting molecular data into a systems perspective.