Literature DB >> 9719396

Alcohol abuse and healing complications after cervical hip fractures.

F Nyquist1, A Overgaard, H Düppe, K J Obrant.   

Abstract

Osteonecrosis of the femoral head following femoral neck fractures is a common condition. Spontaneous osteonecrosis, is, however, a rare disorder, which is observed with increased frequency in alcohol abusers. In this retrospective study, we followed 512 consecutive male patients who had sustained femoral neck fractures between 1984 and 1992; 82 of these 512 patients (16%) had earlier been registered at the Department of Alcohol Diseases as high consumers of alcohol. The aim of the study was to determine the relationship between the rate of healing complications and alcohol consumption. No differences were observed in the degree of fracture dislocation, frequency of femoral head necrosis, and pseudoarthrosis among the abusers. Furthermore, no differences were found in causative events, primary operative treatment, post-operative complications, and the number of secondary operations. The abusers were significantly younger, had a higher rate of early retirement, and had an increased death rate. Our study suggests that alcohol complicates the healing process to a lesser extent than earlier thought, and that osteonecrosis of the femoral head after femoral neck fractures is equally common in non-abusers as in abusers.

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Year:  1998        PMID: 9719396     DOI: 10.1093/oxfordjournals.alcalc.a008407

Source DB:  PubMed          Journal:  Alcohol Alcohol        ISSN: 0735-0414            Impact factor:   2.826


  4 in total

Review 1.  MicroRNAs: master regulators of ethanol abuse and toxicity?

Authors:  Rajesh C Miranda; Andrzej Z Pietrzykowski; Yueming Tang; Pratheesh Sathyan; Dayne Mayfield; Ali Keshavarzian; Wayne Sampson; Dale Hereld
Journal:  Alcohol Clin Exp Res       Date:  2010-01-26       Impact factor: 3.455

2.  A rare case report of peri-implant bone necrosis: Mapping the distance of initial peri-implant complication toward a path of success.

Authors:  S K Salaria; Rajni Aggarwal; Veenu Madaan Hans; Mayank Hans
Journal:  Contemp Clin Dent       Date:  2011-10

3.  Constructing the toolbox: Patient-specific genetic factors of altered fracture healing.

Authors:  Hicham Drissi; David N Paglia; Farhang Alaee; Ryu Yoshida
Journal:  Genes Dis       Date:  2014-12-01

4.  Alcoholism as a predictor for pseudarthrosis in primary spine fusion: An analysis of risk factors and 30-day outcomes for 52,402 patients from 2005 to 2013.

Authors:  Peter G Passias; Cole Bortz; Haddy Alas; Frank A Segreto; Samantha R Horn; Yael U Ihejirika; Dennis Vasquez-Montes; Katherine E Pierce; Avery E Brown; Kartik Shenoy; Edward M DelSole; Bradley Johnson; Cheongeun Oh; Peter L Zhou; Chloe Deflorimonte; Ekhamjeet S Dhillon; Pawel P Jankowski; Bassel G Diebo; Virginie Lafage; Renaud Lafage; Shaleen N Vira; John A Bendo; Jeffrey A Goldstein; Frank J Schwab; Michael C Gerling
Journal:  J Orthop       Date:  2018-12-20
  4 in total

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