Literature DB >> 9718209

The use of whole blood in a dipstick assay for detection of antibodies to Mycobacterium leprae: a field evaluation.

S Bührer-Sekula1, M G Cunha, W A Ferreira, P R Klatser.   

Abstract

We describe a further simplification of a dipstick assay for the detection of antibodies to phenolic glycolipid I of Mycobacterium leprae by using whole blood and evaluated the assay performance in the leprosy endemic area of Amazonas in Brazil. The agreement with the 'gold' standard ELISA was 94.9% (kappa value = 0.87). This simple assay may be useful to identify those at risk of developing leprosy, for example among contacts of leprosy patients at lower levels in the health services.

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Year:  1998        PMID： 9718209     DOI： 10.1111/j.1574-695X.1998.tb01166.x

Source DB:  PubMed          Journal:  FEMS Immunol Med Microbiol        ISSN： 0928-8244


  6 in total

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Journal:  Clin Biochem       Date:  2008-01-03       Impact factor: 3.281

2.  Serology with ML Flow test in health professionals from three different states of Brazil.

Authors:  Karla Lucena Sampaio Calado; Mônica Maria Ferreira Magnanini; Rodrigo Scaliante de Moura; Maria Eugenia Noviski Gallo; Samira Bührer-Sékula; Maria Leide Wand-Del-Rey de Oliveira
Journal:  An Bras Dermatol       Date:  2013 Nov-Dec       Impact factor: 1.896

3.  Nasal mucosa study of leprosy contacts with positive serology for the phenolic glycolipid 1 antigen.

Authors:  Ana Cristina da Costa Martins; Alice Miranda; Maria Leide Wan-del-Rey de Oliveira; Samira Bührer-Sékula; Alejandra Martinez
Journal:  Braz J Otorhinolaryngol       Date:  2010 Sep-Oct

4.  Can baseline ML Flow test results predict leprosy reactions? An investigation in a cohort of patients enrolled in the uniform multidrug therapy clinical trial for leprosy patients in Brazil.

Authors:  Emerith Mayra Hungria; Regiane Morillas Oliveira; Gerson Oliveira Penna; Lúcio Cartaxo Aderaldo; Maria Araci de Andrade Pontes; Rossilene Cruz; Heitor de Sá Gonçalves; Maria Lúcia Fernandes Penna; Ligia Regina Franco Sansigolo Kerr; Mariane Martins de Araújo Stefani; Samira Bührer-Sékula
Journal:  Infect Dis Poverty       Date:  2016-12-06       Impact factor: 4.520

5.  Leprosy reactions: The predictive value of Mycobacterium leprae-specific serology evaluated in a Brazilian cohort of leprosy patients (U-MDT/CT-BR).

Authors:  Emerith Mayra Hungria; Samira Bührer-Sékula; Regiane Morillas de Oliveira; Lúcio Cartaxo Aderaldo; Araci de Andrade Pontes; Rossilene Cruz; Heitor de Sá Gonçalves; Maria Lúcia Fernandes Penna; Gerson Oliveira Penna; Mariane Martins de Araújo Stefani
Journal:  PLoS Negl Trop Dis       Date:  2017-02-21

6.  Mycobacterium leprae-Specific Antibodies in Multibacillary Leprosy Patients Decrease During and After Treatment With Either the Regular 12 Doses Multidrug Therapy (MDT) or the Uniform 6 Doses MDT.

Authors:  Emerith M Hungria; Samira Bührer-Sékula; Regiane M Oliveira; Lúcio C Aderaldo; Maria Araci A Pontes; Rossilene Cruz; Heitor S de Gonçalves; Maria L F Penna; Gerson O Penna; Mariane M A Stefani
Journal:  Front Immunol       Date:  2018-05-14       Impact factor: 7.561
  6 in total

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