Literature DB >> 9718004

Histological study of colonic ischaemia after aortic surgery.

M Welch1, M S Baguneid, R F McMahon, P D Dodd, P E Fulford, G D Griffiths, M G Walker.   

Abstract

BACKGROUND: Colonic ischaemia is a well documented complication of abdominal aortic reconstruction. In this prospective study patients had routine preoperative and postoperative colonoscopy and biopsy, in order to determine the true incidence and implications.
METHODS: Fifty-six patients undergoing elective infrarenal aortic surgery, 28 for aneurysm and 28 for occlusive disease, had colonoscopy and biopsy before and 1 week after operation.
RESULTS: Colonic ischaemia was identified histologically in biopsies from 16 (30 per cent) of 53 patients. Almost half the patients had normal macroscopic appearances. Two factors exhibited a statistically significant association with the development of ischaemia: prolonged cross-clamp time (P < 0.05) and postoperative diarrhoea (P< 0.001). Co-morbidity was much higher in patients with colonic ischaemia (P< 0.005). Overall morbidity was significantly greater in the aneurysm group (P < 0.05).
CONCLUSION: Colonic ischaemia is common after aortic reconstruction. When suspected, colonoscopy with biopsy is diagnostic.

Entities:  

Mesh:

Year:  1998        PMID: 9718004     DOI: 10.1046/j.1365-2168.1998.00791.x

Source DB:  PubMed          Journal:  Br J Surg        ISSN: 0007-1323            Impact factor:   6.939


  4 in total

1.  Clinical investigation of 41 patients with ischemic colitis accompanied by ulcer.

Authors:  Satohiro Matsumoto; Kenichiro Tsuji; Satoshi Shirahama
Journal:  World J Gastroenterol       Date:  2007-02-28       Impact factor: 5.742

2.  Gut barrier dysfunction as detected by intestinal luminal microdialysis.

Authors:  Erik Solligård; Ingebjørg S Juel; Karin Bakkelund; Harald Johnsen; Ola D Saether; Jon Erik Grønbech; Petter Aadahl
Journal:  Intensive Care Med       Date:  2004-02-28       Impact factor: 17.440

3.  Rebamipide enema therapy for left-sided ischemic colitis patients accompanied by ulcers: open label study.

Authors:  Satohiro Matsumoto; Kenichiro Tsuji; Satoshi Shirahama
Journal:  World J Gastroenterol       Date:  2008-07-07       Impact factor: 5.742

Review 4.  Risk factors for ischaemic colitis after surgery for abdominal aortic aneurysm: a systematic review and observational meta-analysis.

Authors:  Matthew J Lee; Sarah L Daniels; Thomas M Drake; Ian J Adam
Journal:  Int J Colorectal Dis       Date:  2016-06-01       Impact factor: 2.571

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.