Literature DB >> 971759

Hypertension mediated by the activation of the rat brain 5-hydroxytryptamine receptor sites.

M K Krstić, D Djurković.   

Abstract

5-Hydroxytryptamine (5-HT) administered intraventricularly (i.vent.) in rats produced hypertension without considerable changes in heart rate. After transsection of the spinal cord or i.vent. administration of methysergide, 5-HT failed to produce the pressor effect. Thus, the hypertension results from the activation of 5-HT receptor sites of the rat brain.

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Year:  1976        PMID： 971759     DOI： 10.1007/BF01927618

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  5 in total

1.  Ability of serotonin and norepinephrine to mimic the central effects of reserpine on vasomotor activity.

Authors:  J W MCCUBBIN; Y KANEKO; I H PAGE
Journal:  Circ Res       Date:  1960-07       Impact factor: 17.367

2.  Inhibition of efferent sympathetic nerve activity by 5-hydroxytryptophan and centrally administered 5-hydroxytryptamine.

Authors:  T Baum; A T Shropshire
Journal:  Neuropharmacology       Date:  1975-03       Impact factor: 5.250

3.  Changes in arterial blood pressure after microinjections of carbachol into the medulla and IVth ventricle of the rat brain.

Authors:  H E Brezenoff; D J Jenden
Journal:  Neuropharmacology       Date:  1970-07       Impact factor: 5.250

4.  The effect of (+)-lysergic acid diethylamide and other drugs on the carotid sinus reflex.

Authors:  K H GINZEL
Journal:  Br J Pharmacol Chemother       Date:  1958-09

5.  The central vasomotor effects of 5-hydroxytryptamie.

Authors:  K P BHARGAVA; K K TANGRI
Journal:  Br J Pharmacol Chemother       Date:  1959-12
  5 in total
  3 in total

1.  Contribution of serotonergic systems to maintenance of blood pressure in anaesthetised normotensive Wistar Kyoto and conscious spontaneously hypertensive rats.

Authors:  B G Schulz; G Schröder; G Stock
Journal:  Drugs       Date:  1988       Impact factor: 9.546

2.  Inhibition of reflex vagal bradycardia by a central action of 5-hydroxytryptophan.

Authors:  A S Tadepalli
Journal:  Br J Pharmacol       Date:  1980-08       Impact factor: 8.739

3.  Central administration of 5-HT activates 5-HT1A receptors to cause sympathoexcitation and 5-HT2/5-HT1C receptors to release vasopressin in anaesthetized rats.

Authors:  I K Anderson; G R Martin; A G Ramage
Journal:  Br J Pharmacol       Date:  1992-12       Impact factor: 8.739
  3 in total

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