Literature DB >> 971744

Alteration of cholesterol synthesis in rat liver as induced by 4-methyl-5-hydroxy valeric acid.

J C Díaz-Zagoya, M E Hurtado, J González.   

Abstract

The rate of cholesterogenesis in rat liver, measured by the incorporation of labelled acetate or mevalonate into cholesterol, was significantly supressed by the use of 4-methyl-5-hydroxy valeric acid sodium salt. This effect cannot be explained by changes in HMG CoA reductase activity.

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Year:  1976        PMID： 971744     DOI： 10.1007/BF01927589

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  10 in total

1.  A simplified method for the estimation of total cholesterol in serum and demonstration of its specificity.

Authors:  L L ABEL; B B LEVY; B B BRODIE; F E KENDALL
Journal:  J Biol Chem       Date:  1952-03       Impact factor: 5.157

2.  Determination of protein: a modification of the Lowry method that gives a linear photometric response.

Authors:  E F Hartree
Journal:  Anal Biochem       Date:  1972-08       Impact factor: 3.365

3.  The effect of two substituted valeric acid derivatives on cholesterol metabolism in rats.

Authors:  D Kritchevsky; S A Tepper; J A Story
Journal:  Proc Soc Exp Biol Med       Date:  1974-01

4.  Fine structure of the cyclic rhythm of 3-hydroxy-3-methylglutaryl coenzyme A reductase. Differential effects of cholesterol feeding and fasting.

Authors:  D J Shapiro; V W Rodwell
Journal:  Biochemistry       Date:  1972-03-14       Impact factor: 3.162

5.  Studies on the regulation of cholesterol metabolism by the use of the structural analogue, diosgenin.

Authors:  J C Díaz Zagoya; J Laguna; J Guzmán-García
Journal:  Biochem Pharmacol       Date:  1971-12       Impact factor: 5.858

6.  Hypolipidaemic properties of a new tetralin derivative (CIBA 13,437-Su).

Authors:  R Hess; W L Bencze
Journal:  Experientia       Date:  1968-05-15

7.  Regulation of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase and cholesterol synthesis.

Authors:  D J Shapiro; V W Rodwell
Journal:  J Biol Chem       Date:  1971-05-25       Impact factor: 5.157

8.  Stimulation of hepatic beta-hydroxy-beta-methylglutaryl coenzyme A reductase activity in hypophysectomized rats by L-triiodothyronine.

Authors:  G C Ness; R E Dugan; M R Lakshmanan; C M Nepokroeff; J W Porter
Journal:  Proc Natl Acad Sci U S A       Date:  1973-12       Impact factor: 11.205

9.  HMG CoA reductase of intestinal mucosa and liver of the rat.

Authors:  S Shefer; S Hauser; V Lapar; E H Mosbach
Journal:  J Lipid Res       Date:  1972-05       Impact factor: 5.922

10.  Stimulatory effect of dietary lipid and cholestyramine on hepatic HMG CoA reductase.

Authors:  S Goldfarb; H C Pitot
Journal:  J Lipid Res       Date:  1972-11       Impact factor: 5.922
  10 in total
  2 in total

1.  Monobutyrin and Monovalerin Affect Brain Short-Chain Fatty Acid Profiles and Tight-Junction Protein Expression in ApoE-Knockout Rats Fed High-Fat Diets.

Authors:  Thao Duy Nguyen; Frida Fåk Hållenius; Xue Lin; Margareta Nyman; Olena Prykhodko
Journal:  Nutrients       Date:  2020-04-24       Impact factor: 5.717

2.  Bioregional Alterations in Gut Microbiome Contribute to the Plasma Metabolomic Changes in Pigs Fed with Inulin.

Authors:  Weida Wu; Li Zhang; Bing Xia; Shanlong Tang; Lei Liu; Jingjing Xie; Hongfu Zhang
Journal:  Microorganisms       Date:  2020-01-13
  2 in total

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